Ethyl acetate extracted from the chinese medicinal plant Caesalpinia sappan L alleviates gustatory response in diabetes mellitus rats.

EtOAc extracts of C. sappan have a beneficial effect on taste-regulatory peptides in vallate papillae and the hypothalamus, suggesting their potential in controlling diseases and possibly improving gustatory response in diabetes mellitus.

Cao X, Cui L and Yang W (2023).

Histol Histopathol.

DOI:

10.14670/HH-18-676

PubMed:

37997936

Discussing pathologic mechanisms of Diabetic retinopathy & therapeutic potentials of curcumin and β-glucogallin in the management of Diabetic retinopathy.

Review explores the pathophysiology of diabetic retinopathy (DR) and the potential of curcumin and β-glucogallin, compounds found in natural sources, to treat and prevent DR. These compounds have shown various health benefits in animal experiments and have been used in traditional herbal medicine.

Rohilla M et al (2023).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2023.115881

PubMed:

37989030

Effects of total flavones of Abelmoschus manihot (L.) on the treatment of diabetic nephropathy via the activation of solute carriers in renal tubular epithelial cells.

Yu H et al (2023).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2023.115899

PubMed:

37984306

Mango (Mangifera indica L.) seed kernel extract suppresses hyperglycemia by modulating pancreatic β cell apoptosis and dysfunction and hepatic glucose metabolism in diabetic rats.

This study found that mango seed kernel extract (MKE) reduced blood glucose levels, improved pancreatic function, and enhanced liver health in diabetic rats. MKE achieved this by reducing inflammation and oxidative damage, and promoting glucose metabolism in the liver.

Yoopum S et al (2023).

Environ Sci Pollut Res Int.

DOI:

10.1007/s11356-023-31066-7

PubMed:

37981611

AR/RKIP pathway mediates the inhibitory effects of icariin on renal fibrosis and endothelial-to-mesenchymal transition in type 2 diabetic nephropathy.

Researchers found that icariin, a compound extracted from Herba epimedium brevicornu maxim, can improve nephropathy disease, supporting the traditional use of this plant and suggesting therapeutic benefits for kidney-related issues.

Yao W et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117414

PubMed:

37977422

Assessing the multitargeted antidiabetic potential of three pomegranate peel-specific metabolites: An in silico and pharmacokinetics study.

In silico study found that three compounds in pomegranate peel (punicalin, punicalagin, and ellagic acid) interacted significantly with nine protein targets involved in diabetes management. These compounds show potential as antidiabetic agents, but further validation is needed.

Gull H et al (2023).

Food Sci Nutr.

DOI:

10.1002/fsn3.3644

PubMed:

37970376

Antidiabetic Activities of 80% Methanol Extract and Solvent Fractions of Verbascum Sinaiticum Benth (Scrophulariaceae) Leaves in Mice.

Study evaluated antidiabetic properties of Benth leaves in mice due to the need for safer and affordable medications. Results may contribute to the discovery of new anti-diabetic drugs.

Dereje B et al (2023).

J Exp Pharmacol.

DOI:

10.2147/JEP.S437991

PubMed:

37964792

Topical Nigella sativa L. product: a new candidate for the management of diabetic peripheral neuropathy.

Study investigates the topical use of Nigella sativa in patients with diabetic neuropathy. N. sativa has shown beneficial effects on neuropathic pain and neurological disorders, offering a potential alternative to synthetic drugs with side effects and limitations.

Khodaie SA et al (2023).

Inflammopharmacology.

DOI:

10.1007/s10787-023-01338-2

PubMed:

37957516