Mulberry leaf's therapeutic effect on type 2 diabetes is confirmed, but we don't know how it works. This study used proteomics to investigate the mechanism in skeletal muscle.
The researchers formulated poly-herbal granules (PHGs) using seeds of and to manage diabetes. The PHGs showed antioxidant and antidiabetic potential due to the presence of flavonoids and phenolic acid derivatives.
A meta-analysis of randomized controlled trials found that purslane supplementation significantly reduced fasting blood glucose levels but had no significant effect on insulin, insulin resistance, or QUICKI levels. However, more high-quality, long-term trials are needed for confirmation.
Researchers found that certain plant materials, like cotton straw, significantly increased the production of polysaccharides with hypoglycemic activity by the fungus Inonotus obliquus, offering insight into ideal materials for polysaccharide synthesis.
This review summarizes the characteristics and uses of mulberry leaves (MLs) in Traditional Chinese Medicine. MLs have multiple bioactive effects that can help treat diabetes and its complications. It serves as a reference for utilizing MLs in preventing and treating diabetes.