Phytochemical profiling and evaluation of the antidiabetic potential of Ichnocarpus frutescens (Krishna Sariva): kinetic study, molecular modelling, and free energy approach.

This research explored antidiabetic properties of a natural herb using enzyme assay and computational approaches. The herb demonstrated promising inhibitory activity against diabetes-related enzymes, with compounds showing better binding energy than a standard drug. The study suggests that the herb could be used as a medication for type 2 diabetes.

Kumari S, Saini R and Mishra A (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2023.2248265

PubMed:

37615387

Hippophae rhamnoides L. leaf extracts alleviate diabetic nephropathy via attenuation of advanced glycation end product-induced oxidative stress in db/db mice.

The study found that sea buckthorn leaf extract (SBL) reduced kidney damage in diabetic mice by decreasing the accumulation of advanced glycation end products (AGEs) and oxidative stress. This suggests that SBL could be a potential treatment for diabetic renal complications.

Gu MJ et al (2023).

Food Funct.

DOI:

10.1039/d3fo01364b

PubMed:

37614189

Therapeutic Potential of Syzygium aromaticum in Gut Dysbiosis via TMAO Associated Diabetic Cardiomyopathy.

Gut bacteria imbalance causes intestinal and other diseases. Specific metabolites (like bile acids and trimethylamine) play a role. Elevated levels of oxidized trimethylamine link to cardiovascular disease. Herbal medicines and prebiotics could help restore balance and improve health.

Singhal S and Rani V (2023).

Cardiovasc Hematol Agents Med Chem.

DOI:

10.2174/1871525721666230822100142

PubMed:

37608671

Clinical and radiographic peri-implant outcomes with riboflavin loaded poly-L-glycolic acid nanoparticles incorporated in aloe vera gel treating peri-implantitis in chronic hyperglycemic patients.

This study compared two treatments for periimplantitis in patients with high blood sugar: antimicrobial photodynamic therapy and riboflavin-loaded nanoparticles in aloe vera gel.

Qamar Z et al (2023).

Photodiagnosis Photodyn Ther.

DOI:

10.1016/j.pdpdt.2023.103752

PubMed:

37595657

Network pharmacology based anti-diabetic attributes of bioactive compounds from Ocimum gratissimum L. through computational approach.

This study identified key compounds in L. plant that target protein molecules of Diabetes Mellitus. These compounds have potential therapeutic effects in managing DM through multiple mechanisms.

Halayal RY et al (2023).

Saudi J Biol Sci.

DOI:

10.1016/j.sjbs.2023.103766

PubMed:

37588570

Antidiabetic effects of polyherbal mixture made of Centaurium erythraea, Cichorium intybus and Potentilla erecta.

Ancient polyherbal mixture with Centaurium erythraea, Cichorium intybus, and Potentilla erecta treats primary and secondary diabetes complications. Potential therapeutic application for diabetes management in the lab.

Petrović A et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117032

PubMed:

37582477

Histologic and Biochemical Effect of Balanite aegyptiaca Fruit Extract on Alloxan-Induced Diabetes in Wistar Rats.

Gamde SM et al (2023).

Ethiop J Health Sci.

DOI:

10.4314/ejhs.v33i3.7

PubMed:

37576166

Lepidium sativum alleviates diabetic nephropathy in a rat model by attenuating glucose levels, oxidative stress, and inflammation with concomitant suppression of TGF-β1.

Whole-plant extract treated diabetic nephropathy in rats by reducing fasting glucose and cholesterol levels, attenuating kidney damage, and decreasing inflammatory markers. Promising therapy for diabetic nephropathy.

Alsuliam SM et al (2023).

Saudi J Biol Sci.

DOI:

10.1016/j.sjbs.2023.103720

PubMed:

37576066