Diabetes Studies

Fortification of Fermented Camel Milk with Salvia officinalis L. or Mentha piperita Leaves Powder and Its Biological Effects on Diabetic Rats.

This study found that fortifying fermented camel milk with sage or mint leaves powder improves glucose and insulin levels, lipid profile, and liver and kidney functions in diabetic rats. Using sage and mint leaves powder with fermented camel milk can create functional food products with anti-diabetic activity.

Shahein MR et al (2023).
Molecules.
PubMed:
37570720

Comprehensive chemo-profiling of coumarins enriched extract derived from Aegle marmelos (L.) Correa fruit pulp, as an anti-diabetic and anti-inflammatory agent.

This study enriched and characterized coumarins from the fruit of the Indian medicinal plant (L.) Correa. The coumarins showed potential as anti-inflammatory and anti-diabetic agents, making them valuable for developing Phytopharmaceutical ingredients.

Tiwari R et al (2023).
Saudi Pharm J.
PubMed:
37564748

Exploration of human pancreatic alpha-amylase inhibitors from Physalis peruviana for the treatment of type 2 diabetes.

This study tested 34 plant-derived flavonoids against pancreatic α-amylase, a drug target for managing Type 2 Diabetes. Four compounds showed promise as antidiabetic candidates.

Tiwari VP et al (2023).
J Biomol Struct Dyn.
PubMed:
37545158

In silico study on antidiabetic and antioxidant activity of bioactive compounds in Ficus carica L.

Study investigated the inhibitory potential of 10 phytochemicals on amylase enzymes through molecular simulations. Results could inform the development of diabetes treatments.

Raman APS et al (2023).
J Biomol Struct Dyn.
PubMed:
37545143

Comparative analysis of antioxidant, antidiabetic and analgesic activity of Callestemon viminalis L. and Alcea rosea L. leaves extracts.

The study compared the antioxidant, antidiabetic, and analgesic activities of extracts from C. viminalis and A. rosea leaves. Both extracts showed significant effects, making them potential treatments for hypercholesteremia, neuropathic pains, and diabetes.

Zafar Ahmed K et al (2023).
Pak J Pharm Sci.
PubMed:
37530154

Fumaria officinalis-loaded chitosan nanoparticles dispersed in an alginate hydrogel promote diabetic wounds healing by upregulating VEGF, TGF-β, and b-FGF genes: A preclinical investigation.

Researchers developed a wound dressing using fumaria officinalis extract-loaded chitosan nanoparticles in a hydrogel. In vitro and in vivo studies showed it promoted cell viability, migration, and wound healing potential comparable to a marketed product. This research suggests potential use in diabetic wound treatment.

Yang X et al (2023).
Heliyon.
PubMed:
37519642

Eucommia lignans alleviate the progression of diabetic nephropathy through mediating the AR/Nrf2/HO-1/AMPK axis in vivo and in vitro.

Eucommia lignans derived from Eucommia ulmoides Oliver have been found to inhibit the progression of diabetic nephropathy (DN) by reducing inflammation and improving renal function through the AR/Nrf2/HO-1/AMPK axis. This suggests that Eucommia lignans could be a potential treatment for DN.

Huang Q et al (2023).
Chin J Nat Med.
PubMed:
37517819