Diabetes Studies

Assessment of antidiabetic, anti-inflammatory, antioxidant and anticancer activity competence of methonolic extracts of Trianthema ortulacastrum and Andrographis paniculata.

Methanol extracts from Andrographis paniculata have more beneficial compounds and higher antioxidant, antidiabetic, and anti-inflammatory activities compared to Trianthema portulacastrum. A. paniculata extract is worth exploring for potential biomedical applications.

CancerDiabetesImmunology Andrographis paniculata
Wadaan MA, Baabbad A and Farooq Khan M (2023).
Environ Res.
DOI:
10.1016/j.envres.2023.117764
PubMed:
38029820

In Vitro Anti-Tumor and Hypoglycemic Effects of Total Flavonoids from Willow Buds.

Willow bud flavonoids showed anti-tumor effects on cervical, colon, and breast cancer cells and displayed hypoglycemic properties, indicating potential applications in food and pharmaceutical industries.

CancerDiabetesPhytochemistry Salix babylonica
Zhang P et al (2023).
Molecules.
DOI:
10.3390/molecules28227557
PubMed:
38005279

Rubia cordifolia L. Attenuates Diabetic Neuropathy by Inhibiting Apoptosis and Oxidative Stress in Rats.

The study investigated the impact of L. (L.) roots in diabetic neuropathy using a rat model. It examined potential neuroprotective, antidiabetic, and analgesic mechanisms. This research is relevant for understanding diabetic neuropathy treatment options.

DiabetesImmunology Rubia cordifolia
Bana S et al (2023).
Pharmaceuticals (Basel).
DOI:
10.3390/ph16111586
PubMed:
38004451

A Berberine-Loaded Bletilla striata Polysaccharide Hydrogel as a New Medical Dressing for Diabetic Wound Healing.

Scientists developed a composite hydrogel dressing for diabetic wounds. The hydrogel demonstrated antibacterial, anti-inflammatory, and antioxidant properties. Animal experiments showed significant acceleration of wound healing. This hydrogel has great potential for clinical use.

Diabetes Bletilla striata
Hu Z et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242216286
PubMed:
38003478

The Effect of Saffron Kozanis (Crocus sativus L.) Supplementation on Weight Management, Glycemic Markers and Lipid Profile in Adolescents with Obesity: A Double-Blinded Randomized Placebo-Controlled Trial.

Saffron supplementation can reduce weight, BMI, and waist circumference in obese prediabetic adolescents, although not as effectively as metformin. It can also improve lipid profiles and has potential as a nutraceutical option for weight management in adolescents with obesity and prediabetes.

DiabetesObesity Crocus sativus
Kotanidou EP et al (2023).
Children (Basel).
DOI:
10.3390/children10111814
PubMed:
38002905

In Vitro and In Vivo Evaluation for Antioxidant and Anti-Diabetic Properties of Cyperus rotundus L. Kombucha.

Kombucha is a fermented beverage with antioxidants that lower oxidative stress, lipid peroxidation, and alpha-glucosidase activity, making it a potential functional food for health.

DiabetesImmunology Cyperus rotundus
Dechakhamphu A et al (2023).
Foods.
DOI:
10.3390/foods12224059
PubMed:
38002116

An in-depth investigation of molecular interaction in zeaxanthin/corn silk glycan complexes and its positive role in hypoglycemic activity.

Corn silk glycans bind to zeaxanthin, creating a complex with bioactive effects. This study reveals the enthalpic force driving this interaction, aiding in understanding the interaction between lipids and glycans in food.

Diabetes Zea mays
Yang L et al (2024).
Food Chem.
DOI:
10.1016/j.foodchem.2023.137986
PubMed:
38000158

Lutein-Rich Beverage Alleviates Visual Fatigue in the Hyperglycemia Model of Sprague-Dawley Rats.

Researchers created a water-soluble lutein beverage with Chinese wolfberry and chrysanthemum that improved crystalline lenses, reduced visual fatigue, and increased antioxidant enzymes in diabetic rats. This beverage is a safe and effective way to enhance anti-oxidation capacity and relieve visual fatigue. (42 words)

Diabetes Tagetes erecta
Tang Q et al (2023).
Metabolites.
DOI:
10.3390/metabo13111110
PubMed:
37999206
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