Diabetes Studies

Diabetic wound healing function of PCL/cellulose acetate nanofiber engineered with chitosan/cerium oxide nanoparticles.

Researchers developed a wound dressing containing chitosan nanoparticles encapsulated with cerium oxide nanoparticles. The dressing demonstrated strong antibacterial properties, antioxidant activity, improved cell viability and migration, and increased diabetic wound repair by 95.47% after 15 days. This has potential for treating diabetes-related wounds.

Diabetes Thymus vulgaris
Kamalipooya S et al (2024).
Int J Pharm.
DOI:
10.1016/j.ijpharm.2024.123880
PubMed:
38350498

Uncovering the Mechanisms of Cinnamic Acid Treating Diabetic Nephropathy Based on Network Pharmacology, Molecular Docking, and Experimental Validation.

Cinnamic acid from Cinnamomum cassia can improve diabetic nephropathy, but we need more understanding of how it works and its potential targets for better treatment.

Diabetes Cinnamomum cassia
Dai L et al (2024).
Curr Comput Aided Drug Des.
DOI:
10.2174/0115734099286283240130115111
PubMed:
38347789

Potential of medicinal plants to ameliorate neovascularization activities in diabetes: A systematic review.

This review examines the potential of medicinal plants to reduce complications of diabetes caused by excessive angiogenesis. Identified plants lowered blood glucose levels and increased body weight, while also decreasing VEGF protein expression and vasculature activity. They have the potential to ameliorate neovascularization activities in diabetes.

Diabetes Tinospora cordifolia
Yong PH et al (2024).
Endocr Regul.
DOI:
10.2478/enr-2024-0004
PubMed:
38345496

Chinese herb couple against diabetes: integrating network pharmacology and mechanism study.

Cassia twig-Astragalus is a Chinese herb couple used to treat diabetes. This study identified its active ingredients and targets, showing potential in improving glucose tolerance and reducing inflammation in diabetic rats.

Diabetes Cinnamomum cassia
Li J et al (2024).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2024.2314263
PubMed:
38345075

Liposomal formulations of Oleae europaea L.: analyzing the antioxidant and antidiabetic activities along with toxicity profile in pancreatic beta TC6 cell line.

A study characterized a plant extract with strong antioxidant and antidiabetic properties. They prepared nanoformulations of the extract and tested their activities. The encapsulation efficiency was high, and the formulations exhibited antioxidant and antidiabetic activity.

DiabetesImmunology Olea europaea
Köngül Şafak E et al (2024).
Int J Environ Health Res.
DOI:
10.1080/09603123.2024.2316848
PubMed:
38344812

Hypoglycemic Effects and Quality Marker Screening of Dendrobium nobile Lindl. at Different Growth Years.

The researchers compared the effects of Lindl. cultivated at year 1 and year 3 on hyperglycemic syndrome in mice. They found that Lindl. from year 1 had a better effect and identified alkaloids as potential quality markers for treating hyperglycemic syndrome.

Diabetes Dendrobium nobile
Luo Y et al (2024).
Molecules.
DOI:
10.3390/molecules29030699
PubMed:
38338442

Preparation of chitosan nanoparticles loaded with Balanites aegyptiaca extract for treatment of streptozotocin-induced diabetes in rats.

Chitosan nanoparticles with Balanites aegyptiaca extract combat diabetes in rats by boosting insulin and reducing blood sugar with antioxidant and anti-inflammatory benefits, offering new treatment possibilities.

Diabetes Balanites aegyptiaca
Alahmer S, El-Noss M and Farid A (2024).
Int J Biol Macromol.
DOI:
10.1016/j.ijbiomac.2024.130061
PubMed:
38336324

Effects of dried okra extract on lipid profile, renal function and some RAGE-related inflammatory genes expression in patients with diabetic nephropathy: A randomized controlled trial.

Study investigated effects of okra extract (DOE) on diabetic nephropathy. DOE supplementation improved lipid profile, renal function, reduced inflammation, and increased sRAGE levels in patients with DN.

DiabetesGeneticsImmunology Abelmoschus esculentus
Bahreini N et al (2024).
Complement Ther Med.
DOI:
10.1016/j.ctim.2024.103027
PubMed:
38336011
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