Diabetes Studies

Effectiveness of Ya-Samarn-Phlae in diabetic wound healing: Evidence from in vitro studies and a multicenter randomized controlled clinical trial.

Traditional Thai medicine Ya-Samarn-Phlae (YaSP) used for wounds, particularly diabetic foot ulcers. Study validates clinical use, identifies chemical markers, and evaluates wound healing properties. Important for evidence-based medicine and development of new treatments.

Sanpinit S et al (2024).
J Ethnopharmacol.
PubMed:
38373661

Synergistic anti-diabetic effect of phloroglucinol and total procyanidin dimer isolated from Vitisvinifera methanolic seed extract potentiates via suppressing oxidative stress: in-vitro evaluation studies.

Researchers identified and purified phloroglucinol and total procyanidin dimer from seed extract, showing superior anti-diabetic effects in vitro by enhancing glucose uptake and suppressing oxidative stress. This natural remedy could offer a safe and economical alternative to current diabetes treatments.

Thupakula S et al (2024).
3 Biotech.
PubMed:
38371900

Andaliman (Zanthoxylum acanthopodium DC.) fruit ethanolic extract exerts attenuative effect on hyperglycemia, sensory and motoric function's disorders in alloxan-induced diabetic mice.

Andaliman fruit extract effectively reduces hyperglycemia and improves balance in diabetic mice, potentially offering benefits for diabetes treatment and neuroprotection.

Santoso P et al (2023).
J Adv Vet Anim Res.
PubMed:
38370902

Effect of Cucurbita ficifolia Bouché on glutathione level and glycosylated hemoglobin percentage in a Mexican rural population with type 2 diabetes.

Researchers found that Cucurbita ficifolia fruit has antioxidant and hypoglycemic properties, beneficial for treating type 2 diabetes. GSH imbalance can lead to complications.

Hernandez-Mixteco M et al (2024).
J Ethnopharmacol.
PubMed:
38369067

The Phenolic Content of Pistacia lentiscus Leaf Extract and Its Antioxidant and Antidiabetic Properties.

This study examined the polyphenolic profile of leaves and their potential antioxidant and antidiabetic activities. The extract showed high levels of phenolic and flavonoid compounds and demonstrated significant inhibition of pancreatic alpha-amylase activity. This suggests potential benefits for diabetes treatment.

Bouakline H et al (2024).
ScientificWorldJournal.
PubMed:
38356989

A network pharmacology, molecular docking and in vitro investigation of Picrorhiza kurroa extract for the treatment of diabetic nephropathy.

A study investigated the potential of Royle ex Benth. (PK/Kutki) herb for the treatment of diabetic nephropathy. Network pharmacology and molecular docking were used to identify bioactive compounds, targets, and pathways involved. The herb showed promising effects on DN, suggesting its potential as a treatment option.

Pal S et al (2024).
J Biomol Struct Dyn.
PubMed:
38356141

Unveiling the chemical profiling and remarkable modulation of carbohydrate metabolism by costus root, Dolomiaea costus (Falc.) in streptozotocin (STZ)-Induced diabetic rats.

Dolomiaea costus is a medicinal plant with multiple therapeutic properties, such as anti-inflammatory, antiseptic, and antidiabetic effects. It has been used in various indigenous medicine systems.

Abouelwafa E et al (2024).
J Ethnopharmacol.
PubMed:
38355028

Corrigendum to "2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione, isolated from the root of Averrhoa carambola L., protects against diabetic kidney disease by inhibiting TLR4/TGFβ signaling pathway" [Int. Immunopharmacol. 80 (2020) 106120].

Zhang H et al (2024).
Int Immunopharmacol.
PubMed:
38350758