Phenolic enriched fraction of Clerodendrum glandulosum Lindl. leaf extract ameliorates hyperglycemia and oxidative stress in streptozotocin-nicotinamide induced diabetic rats.

Study evaluates the anti-diabetic and antioxidant effects of Clerodendrum glandulosum leaf extract. Identified major bioactive compounds and their molecular interactions with target proteins. Relevant for potential treatment of diabetes and associated complications.

Khound P et al (2024).

J Ayurveda Integr Med.

DOI:

10.1016/j.jaim.2024.100906

PubMed:

38761758

Metabolic profiling reveals the nutraceutical effect of Gongolaria abies-marina and Rosmarinus officinalis extracts in a type 1 diabetes animal model.

Study found R. officinalis and G. abies-marina extracts can positively impact metabolic profile in diabetic rats. G. abies-marina had stronger effect. Potential for managing diabetes-related metabolic issues.

Godzien J et al (2024).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2024.116731

PubMed:

38761421

The Impact of Red Beetroot Products on Glycemic Profiles: A Systematic Review of Human Evidence.

Alhalabi B, Joseph A and Kumar D (2024).

Curr Nutr Rep.

DOI:

10.1007/s13668-024-00546-8

PubMed:

38760619

A single-cell profile reveals the transcriptional regulation responded for Abelmoschus manihot (L.) treatment in diabetic kidney disease.

HKC, from Abelmoschus manihot, treats diabetic kidney disease. Key flavonoids in HKC include rutin, hyperoside, and quercetin. Important for DKD treatment.

Wu C et al (2024).

Phytomedicine.

DOI:

10.1016/j.phymed.2024.155642

PubMed:

38759315

Effect of Ducrosia anethifolia methanol extract against methicillin resistant Staphylococcus aureus and Pseudomonas aeruginosa biofilms on excision wound in diabetic mice.

Saudi plant, Z. spina-christi, treats skin infections in folk medicine. Widely available in Middle East. Potential natural remedy for lab research.

Almuhanna Y et al (2024).

Front Cell Infect Microbiol.

DOI:

10.3389/fcimb.2024.1386483

PubMed:

38756229

Alpha-cyperone mitigates renal ischemic injury via modulation of HDAC-2 expression in diabetes: Insights from molecular dynamics simulations and experimental evaluation.

Alpha-cyperone from Cyperus rotundus protects kidneys of diabetic rats from injury by reducing oxidative stress, inflammation, and inhibiting HDAC-2 activity. Promising potential treatment for diabetic kidney damage.

Daude RB, Bhadane R and Shah JS (2024).

Eur J Pharmacol.

DOI:

10.1016/j.ejphar.2024.176643

PubMed:

38754539

A network pharmacology-based method to explore the therapeutic effect of honokiol on diabetes with comorbid depression in mice.

Honokiol from Magnolia officinalis may help treat diabetes with depression by activating RXR/VDR heterodimer. This could restore autophagy balance and improve neuroplasticity in the hippocampus.

Sun H et al (2024).

Eur J Pharmacol.

DOI:

10.1016/j.ejphar.2024.176642

PubMed:

38754538

Standardization parameters and synergism of source plant materials for the antidiabetic efficacy of the Rauvolfia-Citrus tea.

TL;DR: Standardized herbal RC-tea from Rauvolfia-Citrus treats T2D with blood glucose control and lipid reduction. Mix of both plants essential for best results, avoiding hypoglycemia or hyperglycemia. Ideal, cost-effective alternative to GLP-1 treatments in low-income areas with rising T2D rates.

Campbell-Tofte J et al (2024).

Fitoterapia.

DOI:

10.1016/j.fitote.2024.106004

PubMed:

38744382