Diabetes Studies

Efficacy and safety of Plantago major seeds in patients with diabetic nephropathy: A randomized open-labeled controlled clinical trial.

Study aims to investigate the efficacy of Plantago major seed powder in diabetic nephropathy patients. Plantain may help improve albuminuria and GFR decline in these individuals.

Haider R et al (2024).
Explore (NY).
PubMed:
38797623

Undescribed Cyclohexene and Benzofuran Alkenyl Derivatives from Choerospondias axillaris, a Potential Hypoglycemic Fruit.

Scientists isolated 18 compounds from south wild jujube fruits, including new and known derivatives. These compounds showed significant inhibitory activity on α-glucosidase, suggesting potential as hypoglycemic bioactive components for functional foods.

Weldetsadik ET et al (2024).
Foods.
PubMed:
38790795

Effects of Momordica charantia L. supplementation on glycemic control and lipid profile in type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials.

The study reviewed L. () for managing type 2 diabetes. Results show it improves glycemic indexes and lipid profile in patients. Important for T2DM treatment.

Zhang X et al (2024).
Heliyon.
PubMed:
38784554

Efficacy and safety of traditional Chinese medicine decoction as an adjuvant treatment for diabetic nephropathy: a systematic review and meta-analysis of randomized controlled trials.

Study shows traditional Chinese medicine decoction as adjunctive treatment for diabetic nephropathy improves clinical efficacy without increasing adverse events. Combined with western medicine, it enhances therapeutic effects. Top herbs include Astragali radix and Salviae miltiorrhizae.

Zheng S et al (2024).
Front Pharmacol.
PubMed:
38783937

Puerarin mitigated LPS-ATP or HG-primed endothelial cells damage and diabetes-associated cardiovascular disease via ROS-NLRP3 signalling.

Puerarin (Pue) from Pueraria lobata protects against vascular damage induced by diabetes by reducing inflammation and oxidative stress through inactivating the ROS-NLRP3 signaling pathway. This could potentially lead to new treatments for diabetic vascular diseases.

Wei H et al (2024).
J Cell Mol Med.
PubMed:
38774996

Momordica charantia Bioactive Components: Hypoglycemic and Hypolipidemic Benefits Through Gut Health Modulation.

MC from the Cucurbitaceae family has hypoglycemic and hypolipidemic properties due to bioactive compounds. Studies show regulatory effects on glycolipid metabolism. Review highlights its components and potential as a nutrient supplement.

Xiao X et al (2024).
J Med Food.
PubMed:
38770678

Antidiabetic Properties of Caffeoylmalic Acid, a Bioactive Natural Compound Isolated from Urtica dioica.

Tossers tested caffeoylmalic acid from Urtica dioica for antidiabetic activity. Results showed potential as a novel treatment for type 2 DM, reducing blood glucose levels and improving lipid and blood parameters.

Rehman G et al (2024).
Fitoterapia.
PubMed:
38763410

SIRT1/AMPK-mediated pathway: Ferulic acid from sugar beet pulp mitigating obesity-induced diabetes-linked complications and improving metabolic health.

Sugar beet pulp extract (SBP-E) from ferulic acid reduces oxidative stress, improves glucose and lipid metabolism, and decreases inflammation in obesity-induced type 2 diabetes. SBP-E activates SIRT1/AMPK signaling and modulates the AMPK/SREBP1/ACC1 pathway, offering potential treatment benefits.

Singh SSB and Patil KN (2024).
Biochim Biophys Acta Mol Cell Biol Lipids.
PubMed:
38761896