Extract of Cimicifuga racemosa (L.) Nutt protects ovarian follicle reserve of mice against in vitro deleterious effects of dexamethasone.
CIMI extract counteracts the harmful effects of DEXA on mouse ovaries in vitro, maintaining follicle morphology, stromal cellular density, and gene expression levels of Bax, Bcl-2, and Caspase-3 similar to control. CIMI can protect ovaries from DEXA-induced damage.
- Assis EIT et al (2023).
- Braz J Med Biol Res.
- PubMed:
- 37792779