Endocrinology Studies

In-silico studies of Brassica oleracea active compounds and their role in thyroid peroxidase activity.

Scientists studied the potential anti-thyroid effects of compounds in cabbage. Only 18 out of 60 compounds showed strong binding with the target. Gamma-Terpinene, a monoterpene, had the highest binding energy and met all criteria. Cooked cabbage might have diminished anti-thyroid effects due to the degradation of gamma-Terpinene.

Kalath H et al (2023).
J Biomol Struct Dyn.
PubMed:
37870072

YIV-818-A: a novel therapeutic agent in prostate cancer management through androgen receptor downregulation, glucocorticoid receptor inhibition, epigenetic regulation, and enhancement of apalutamide, darolutamide, and enzalutamide efficacy.

YIV-818-A, a botanical drug derived from Rubia cordifolia extracts, effectively inhibits castration-resistant prostate cancer (CRPC) and shows synergy with existing drugs. It has potential as an anti-prostate cancer drug with chemopreventive properties.

Lam W et al (2023).
Front Pharmacol.
PubMed:
37860121

Vitagnus an estrogen-riched herbal remedy used in sexual dysfunction: A randomized clinical trial.

Study in Iran: Vitagnus, a herb with phytoestrogens, evaluated for treating sexual dysfunction in postmenopausal women. Results indicated potential efficacy in improving sexual dysfunction.

Zohreh A et al (2023).
J Educ Health Promot.
PubMed:
37849864

Exogenous auxin regulates the growth and development of peach fruit at the expansion stage by mediating multiple-hormone signaling.

Researchers investigated the molecular regulatory network during auxin-mediated peach fruit expansion, an important stage for fruit yield and quality. Understanding this network can help optimize fruit production and improve crop quality.

Zhang Y et al (2023).
BMC Plant Biol.
PubMed:
37848815

Benefits of basil tea for patients with differentiated thyroid cancer during radioiodine therapy: A randomized controlled trial.

Researchers investigated the psychological and physical effects of radioactive iodine therapy for thyroid cancer patients, highlighting the importance of considering both aspects for better patient care.

Nomura K, Nakayama M and Okizaki A (2023).
Heliyon.
PubMed:
37829808

[Effects of Exogenous Plant Hormone Spraying on the Phytoremediation by Bidens pilosa L. in Cadmium-contaminated Soil].

Spraying the plant hormone SA on hyperaccumulated plants can enhance their ability to absorb heavy metals, improve plant growth, increase photosynthesis, and strengthen antioxidant capacity. Among the hormones tested, foliar spraying with 30 mg·L SA had the best effect.

Yang Q et al (2023).
Huan Jing Ke Xue.
PubMed:
37827791

In-vitro Antioxidant, In-vitro and In-silico Ovarian Anticancer Activity (Ovarian Cancer Cells-PA1) and Phytochemical Analysis of Cissus quadrangularis L. Ethanolic Extract.

Research shows that Cissus quadrangularis, a plant, holds medicinal properties. This information is relevant for making informed decisions in the field of traditional medicine.

Zhao X et al (2023).
Comb Chem High Throughput Screen.
PubMed:
37818574

The acute effects of exercise intensity and inorganic nitrate supplementation on vascular health in females after menopause.

Nitric oxide supplementation with beetroot juice + high-intensity exercise improves vascular function in postmenopausal females, potentially offering alternative to those unwilling to perform high-intensity exercise. Future studies could explore long-term benefits.

Hogwood AC et al (2023).
J Appl Physiol (1985).
PubMed:
37795531