Endocrinology Studies

Chia (Salvia hispanica L.) can directly suppress basic ovarian cell functions in two farm animal species and protect ovarian cells from the proliferation-stimulating influence of xylene.

Chia seed extract reduced markers of cell function in bovine and porcine ovarian cells. Xylene stimulated proliferation and hormones release but chia mitigated its effects on cell proliferation. Chia could be a natural protector against xylene's effects on ovarian cells.

Tarko A et al (2023).
Reprod Domest Anim.
PubMed:
37017149

Chamomile and Urtica dioica extracts improve immunological and histological alterations associated with polycystic ovarian syndrome in DHEA -induced mice.

This study explores the immune-modulating effects of chamomile and nettle, traditionally used to treat gynecological diseases, in the pathogenesis of Polycystic ovary syndrome (PCOS).

Shamsi M et al (2023).
BMC Complement Med Ther.
PubMed:
37013510

A Review of Clinical and Preclinical Studies on the Therapeutic Potential of Black Seeds (Nigella sativa) in the Management of Polycystic Ovarian Syndrome (PCOS).

This review article explores the potential use of traditional herbal medicine to manage polycystic ovary syndrome (PCOS) in women due to its increasing prevalence and the high use of herbal medicine globally.

Balasubramanian R et al (2023).
J Pharmacopuncture.
PubMed:
37007297

Safranal inhibits estrogen-deficiency osteoporosis by targeting Sirt1 to interfere with NF-κB acetylation.

Safranal, derived from Saffron, has anti-inflammatory properties. Its role in osteoporosis, a bone disease in menopause, and its effect on osteoclasts regulated by NF-κB signaling is unknown.

Sheng SR et al (2023).
Phytomedicine.
PubMed:
37004404

Synaptoporin and parathyroid hormone 2 as markers of multimodal inputs to the auditory brainstem.

Researchers investigated the distribution of the synaptic vesicle protein synaptoporin in the mouse brainstem. They found region-specific differences in its accumulation, with higher levels in areas known to receive extra-auditory inputs. They also identified synaptoporin-positive synapses in the auditory system and traced their origin to the medial paralemniscal nucleus, which uses parathyroid hormone 2 as a transmitter. The study suggests that different inputs work together in the superior olivary complex.

Reuss S et al (2023).
J Chem Neuroanat.
PubMed:
36958466