Endocrinology Studies

Hormonal crosstalk controls cell death induced by kinetin in roots of Vicia faba ssp. minor seedlings.

This study investigates the hormonal background of kinetin-regulated cell death in the cortex of faba bean roots. Results suggest that specific hormone interactions induce cell death, providing a valuable model for further studies on plant cell death.

Kaźmierczak A et al (2023).
Sci Rep.
PubMed:
37468550

The role of oxidative stress in chemotherapy-induced gonadotoxicity in a rat model, and the protective effects of Nigella Sativa oil on oxidative stress, the anti-Müllerian hormone level, and apoptosis.

Study investigated the impact of oxidative stress on carboplatin-induced damage to the ovaries. Found that Nigella Sativa oil has a protective effect by reducing apoptosis and restoring anti-Müllerian hormone levels. Important for understanding potential strategies to mitigate chemotherapy-induced reproductive toxicity.

Cetinkaya K et al (2023).
Eur Rev Med Pharmacol Sci.
PubMed:
37458651

Effects of Withania somnifera (Ashwagandha) on Hematological and Biochemical Markers, Hormonal Behavior, and Oxidant Response in Healthy Adults: A Systematic Review.

Summary: This review evaluated the current evidence on the health benefits of Withania somnifera (Ws) supplementation in healthy adults. Most studies reported that Ws supplementation reduced oxidative stress and inflammation, regulated hormone levels, and had no serious adverse events. However, more research is needed to fully understand its application.

Gómez Afonso A et al (2023).
Curr Nutr Rep.
PubMed:
37428341

The Effect and Safety Assessment of Metformin and DLBS3233 (A Bioactive Fraction of Lagerstroemia speciosa and Cinnamomum burmannii) on Improving Metabolic Parameters in Women with Polycystic Ovary Syndrome.

This study tested the effectiveness and safety of DLBS3233, a new insulin-sensitizing drug derived from Indonesian herbals, alone and in conjunction with metformin, in women with PCOS and insulin resistance.

Hidayat ST et al (2023).
Int J Womens Health.
PubMed:
37424700

Integrated physicochemical, hormonal, and transcriptomic analysis reveals the underlying mechanism of callus formation in Pinellia ternata hydroponic cuttings.

Researchers developed a highly efficient cultivation technology for hydroponic cuttings of a medicinal herb. It increases seedling production rate and addresses issues in traditional cultivation methods. However, the callus formation mechanism in hydroponic cuttings is still unclear.

Duan X et al (2023).
Front Plant Sci.
PubMed:
37409296

Metal-organic framework-encapsulated dihydroartemisinin nanoparticles induces apoptotic cell death in ovarian cancer by blocking ROMO1-mediated ROS production.

Researchers developed ZIF-DHA nanoparticles to enhance the anticancer properties of dihydroartemisinin (DHA) by improving its delivery to ovarian cancer cells and reducing cellular reactive oxygen species. The study suggests that ZIF-DHA nanoparticles could be a promising treatment for ovarian cancer. (40 words)

Yan Y et al (2023).
J Nanobiotechnology.
PubMed:
37386404

Incredible Combination of Lifestyle Modification and Herbal Remedies for Polycystic Ovarian Syndrome Management.

Researchers reviewed the use of yoga and herbal remedies for polycystic ovarian syndrome (PCOS), a common hormonal disorder. These alternative therapies can help improve symptoms and quality of life, offering a holistic approach to PCOS management. Further research is needed to validate these findings.

Balkrishna A et al (2023).
Evid Based Complement Alternat Med.
PubMed:
37383339