Gastroenterology Studies

Prediction of potential mechanisms of rhubarb therapy for colorectal cancer based on network pharmacological analysis and molecular docking.

Study investigated potential targets and mechanism of Rheum palmatum L in treating colorectal cancer using network pharmacology and molecular docking. Identified key targets and components, suggesting potential therapeutic benefits through regulating multiple signaling pathways in colorectal cancer.

Yang F et al (2024).
Medicine (Baltimore).
PubMed:
38518016

Traditional Chinese medicine for gastric cancer: An evidence mapping.

Chinese Medicine has potential benefits for gastric cancer treatment, improving survival, myelosuppression, and immune function. More rigorous studies are needed, but integrating these interventions into clinical care may be beneficial.

Dai Z et al (2024).
Phytother Res.
PubMed:
38517014

Antidepressant-like effects of hyperin on chronic stress-induced depressive-like behaviors in mice: Gut microbiota and short-chain fatty acids.

Study investigates hyperoside from Hypericum perforatum for antidepressant effects. Results will help understand effectiveness for depression treatment.

Song A et al (2024).
J Affect Disord.
PubMed:
38492650

Notoginsenoside R1 promotes Lgr5(+) stem cell and epithelium renovation in colitis mice via activating Wnt/β-Catenin signaling.

NGR1 from Panax notoginseng repairs damaged intestinal barrier in colitis mice by promoting Lgr5 stem cells through Wnt signaling pathway, reducing inflammation and enhancing epithelial repair. Potential therapeutic for IBD.

Yu ZL et al (2024).
Acta Pharmacol Sin.
PubMed:
38491161