Gastroenterology Studies

Components from Curcuma longa (Turmeric) Against Hepatobiliary Diseases Based on Gut-Liver Axis: Pharmacotherapeutic Properties and Potential Clinical Applications.

Turmeric regulates gut-liver axis to treat hepatobiliary diseases. Safe, effective, with potential clinical benefits. More research needed for clinical application.

Gao T et al (2024).
Am J Chin Med.
PubMed:
38490808

Gypenoside induces apoptosis by inhibiting the PI3K/AKT/mTOR pathway and enhances T-cell antitumor immunity by inhibiting PD-L1 in gastric cancer.

Gypenoside induces apoptosis in gastric cancer cells, inhibits PI3K/AKT/mTOR pathway, and reduces PD-L1 expression. Enhances antitumor immunity of T cells. Potential new therapeutic agent for immunotherapy in gastric cancer.

Wu H et al (2024).
Front Pharmacol.
PubMed:
38482051

Homotherapy-for-heteropathy of Bupleurum Chinense DC.-Scutellaria baicalensis Georgi in treating depression and colorectal cancer: A network pharmacology and animal model approach.

BS drug pair is effective for depression and tumor treatment, but simultaneous targeting mechanism remains unclear. Understanding could lead to new treatment approaches for both conditions.

Sun R et al (2024).
J Ethnopharmacol.
PubMed:
38479544

A Randomized, Double-Blind, Placebo-Controlled Trial: Efficacy of Opuntia ficus-indica Prebiotic Supplementation in Subjects with Gut Dysbiosis.

Study showed that Odilia extract improves gut microbiota, reduces inflammation, and alleviates gastrointestinal discomfort in adults with gut dysbiosis. Odilia supplementation may be a beneficial treatment for gut health.

Mellai M et al (2024).
Nutrients.
PubMed:
38474715