Carboxymethylated Abrus cantoniensis polysaccharide prevents CTX-induced immunosuppression and intestinal damage by regulating intestinal flora and butyric acid content.

Hu H et al (2024).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2024.129590

PubMed:

38266859

Uncovering the colorectal cancer immunotherapeutic potential: Evening primrose (Oenothera biennis) root extract and its active compound oenothein B targeting the PD-1/PD-L1 blockade.

Immune checkpoint inhibitors (such as PD-L1/PD-1 blockers) are effective immunotherapy drugs for cancer treatment, but their side effects restrict their use. FDA only permits monoclonal antibody-based PD-L1/PD-1 blockers.

Lee EJ et al (2024).

Phytomedicine.

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10.1016/j.phymed.2024.155370

PubMed:

38266440

Elephantopus scaber L. Polysaccharides Alleviate Heat Stress-Induced Systemic Inflammation in Mice via Modulation of Characteristic Gut Microbiota and Metabolites.

Wang C et al (2024).

Nutrients.

DOI:

10.3390/nu16020262

PubMed:

38257155

Eugenol Reduced ΜPO, CD45 and HMGB1 Expression and Attenuated the Expression of Leukocyte Infiltration Markers in the Intestinal Tissue in Biliopancreatic Duct Ligation-Induced Pancreatitis in Rats.

Oikonomou P et al (2023).

Medicina (Kaunas).

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10.3390/medicina60010074

PubMed:

38256335

Dietary purple potato supplement attenuates DSS-induced colitis in mice: impact on mitochondrial function.

Sun Q et al (2024).

J Nutr Biochem.

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10.1016/j.jnutbio.2024.109585

PubMed:

38253109

A Prunus avium L. Infusion Inhibits Sugar Uptake and Counteracts Oxidative Stress-Induced Stimulation of Glucose Uptake by Intestinal Epithelial (Caco-2) Cells.

Barreto-Peixoto JA et al (2023).

Antioxidants (Basel).

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10.3390/antiox13010059

PubMed:

38247483

Daily Cashew and Brazil Nut Consumption Modifies Intestinal Health in Overweight Women on Energy-Restricted Intervention: A Randomized Controlled Trial (Brazilian Nuts Study).

Researchers studied the relationship between obesity, intestinal health, and the consumption of nuts. They found that nuts can improve gut health, reduce inflammation, and enhance the benefits of weight loss.

Souza Silveira BK et al (2024).

J Nutr.

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10.1016/j.tjnut.2023.12.022

PubMed:

38246355

Triptolide induces apoptosis and cytoprotective autophagy by ROS accumulation via directly targeting peroxiredoxin 2 in gastric cancer cells.

Triptolide, an active compound from Tripterygium wilfordii, kills gastric cancer cells by increasing reactive oxygen species (ROS) levels. It targets peroxiredoxins-2 (PRDX2) to inhibit its antioxidant activity, leading to apoptosis. PRDX2 could be a potential therapeutic target for anti-gastric cancer agents.

Chen P et al (2024).

Cancer Lett.

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10.1016/j.canlet.2024.216622

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38246224