Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity.

Hinokitiol from Chamaecyparis obtusa and Thuja plicata protects against ethanol-induced gastric injury by reducing hemorrhagic lesions and inflammation. It does this by regulating cellular iron levels, suggesting it could be used to prevent or improve gastric injury.

Zhao M et al (2024).

Eur J Pharmacol.

DOI:

10.1016/j.ejphar.2024.176340

PubMed:

38244759

Morphological, Biochemical and Molecular Docking Evaluation of the Anti-inflammatory Effects of Methanolic Extract of Bridelia ferruginea stem bark on Acetic acid-induced Ulcerative Colitis in Rats.

Oluwagbamila OB et al (2023).

Niger J Physiol Sci.

DOI:

10.54548/njps.v38i1.12

PubMed:

38243362

Corrigendum to "The traditional herb Sargentodoxa cuneata alleviates DSS-induced colitis by attenuating epithelial barrier damage via blocking necroptotic signaling" [J. Ethnopharmacol. 319P3 (2024) 117373].

Wang Y et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.117761

PubMed:

38237254

Effects of Sichuan pepper (huājiāo) powder on disease activity and caecal microbiota of dextran sodium sulphate-induced inflammatory bowel disease mouse model.

Sichuan pepper (huājiāo) has strong antioxidant and bile acid-lowering properties. It also modulates inflammation-related cytokines and gut microbiota in mice on a low-fiber, high-sucrose diet.

Miyashita A et al (2024).

Mol Biol Rep.

DOI:

10.1007/s11033-023-09103-y

PubMed:

38236446

Pumpkin seeds (Cucurbita pepo subsp. ovifera) decoction promotes Trichinella spiralis expulsion during intestinal phase via "Weep and Sweep" mechanism.

This study tested the impact of pumpkin decoction on Trichinella spiralis in mice. Pumpkin decoction, especially when combined with honey, significantly reduced adult worm count, improved immune response, and decreased histological changes. Pumpkin decoction could be a promising alternative treatment for T. spiralis.

Saleh AS et al (2024).

Sci Rep.

DOI:

10.1038/s41598-024-51616-4

PubMed:

38233460

Triptolide inhibits proliferation and invasion of colorectal cancer cells by blocking Nrf2 expression.

Triptolide (TPL) from Tripterygium wilfordii inhibits colorectal cancer (CRC) cell growth and invasion. It promotes cell death and reduces the levels of MMP-2 and MMP-9. The mechanism involves inhibition of Nrf2 signaling.

Wang HF and Zhao ZL (2024).

Chem Biol Drug Des.

DOI:

10.1111/cbdd.14410

PubMed:

38230794

Polysaccharide from Panax japonicus C.A. Mey prevents non-alcoholic fatty liver disease development based on regulating liver metabolism and gut microbiota in mice.

Wu Y et al (2024).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2024.129430

PubMed:

38228199

Phytochemical Properties of Crataegus azarolus Berries Decoction Extract and Evaluation of its Protective Activity Against Acetic Acid-Induced Ulcerative Colitis in Rats.

The researchers found that the extract from berries had a protective effect against ulcerative colitis induced by acetic acid in rats. The extract showed antioxidant activity and reduced damage to the colon by stimulating mucus secretion and reducing inflammation. This suggests that the extract could be a potential treatment for ulcerative colitis.

Sammari H et al (2024).

Dose Response.

DOI:

10.1177/15593258241226890

PubMed:

38223297