Gastroenterology Studies

Discovery of Artemisinins as Microsomal Prostaglandins Synthase-2 Inhibitors for the Treatment of Colorectal Cancer via Chemoproteomics.

Artemisinin, an active compound from a Chinese herb, inhibits colorectal cancer cell growth by targeting microsomal prostaglandins synthase-2, reducing prostaglandin E biosynthesis. This discovery could lead to new treatments for colon cancer.

Geng Y et al (2024).
J Med Chem.
PubMed:
38287228

Unlocking the potential of Rosa roxburghii Tratt polyphenol: a novel approach to treating acute lung injury from a perspective of the lung-gut axis.

Researchers found that polyphenols from Rosa roxburghii Tratt plant can prevent and treat acute lung injury (ALI) in mice by regulating gut microbiota. This suggests the potential of using functional foods to alleviate ALI and improve gut health.

Tang L et al (2024).
Front Microbiol.
PubMed:
38282971

Effects of the compound extracts of Caprifoliaceae and Scutellaria baicalensis Georgi on the intestinal microbiota and antioxidant function.

This study investigated the antioxidant, anti-inflammatory, and intestinal protective properties of and Georgi extracts. Results showed potential health benefits on body weight, intestinal microbiota, and short-chain fatty acid concentrations. Useful for clinical and animal production applications.

Zhang S et al (2024).
Front Microbiol.
PubMed:
38282732