GeoBotanical: Gastroenterology Studies

441.

Identification of Differentially Expressed Genes in Human Colorectal Cancer Using RNASeq Data Validated on the Molecular Level with Real-Time PCR.

Bioinformatics tools identified early detection biomarkers for colorectal cancer and explored plant extract as a chemotherapy alternative. Three diagnostic markers identified, with positive trends in gene expression and therapeutic value. Further trials required. Precise and robust analysis workflow valuable for CRC diagnosis and treatment decisions.

Cancer Gastroenterology Genetics Withania somnifera

Elsayed AMA et al (2023).; Biochem Genet.
DOI:: 10.1007/s10528-023-10593-5
PubMed:: 38097858

442.

Bio-valorization of Tagetes floral waste extract in fabrication of self-healing Schiff-base nanocomposite hydrogels for colon cancer remedy.

Floral waste from marigold flowers is used to create a hydrogel that has self-healing ability, enhanced antioxidant and anti-inflammatory properties, and controlled release of a drug for colorectal cancer treatment. This study highlights the potential of using floral waste for colon cancer remedy.

Cancer Gastroenterology Tagetes erecta

Dalei G et al (2023).; Environ Sci Pollut Res Int.
DOI:: 10.1007/s11356-023-31392-w
PubMed:: 38097839

443.

Effects of pomegranate (Punica granatum L.) peel on the growth performance and intestinal microbiota of broilers challenged with Escherichia coli.

Gastroenterology Punica granatum

Xu P et al (2024).; Poult Sci.
DOI:: 10.1016/j.psj.2023.103304
PubMed:: 38096668

444.

Correction: Preparation of Self-microemulsion Solids of Kaempferia galanga (L.) Volatile Oil and Its Effect on Rats with Gastric Ulcer.

Gastroenterology Kaempferia galanga

Liu D et al (2023).; AAPS PharmSciTech.
DOI:: 10.1208/s12249-023-02719-0
PubMed:: 38093162

445.

Total flavones from Sonchus arvensis L. ameliorate colitis by adjusting the gut microbiota.

Gastroenterology Sonchus arvensis

Ren Y et al (2023).; Ann Med.
DOI:: 10.1080/07853890.2023.2292246
PubMed:: 38091956

446.

Potential anticancer properties and mechanisms of thymoquinone in colorectal cancer.

Thymoquinone (TQ) from Nigella sativa has anti-cancer properties against colorectal cancer. It can enhance existing cancer treatments and reduce adverse effects. More research is needed to understand its molecular targets and improve its clinical usefulness in overcoming drug resistance and obstacles in chemotherapy and radiotherapy.

Cancer Gastroenterology Nigella sativa

Sheikhnia F et al (2023).; Cancer Cell Int.
DOI:: 10.1186/s12935-023-03174-4
PubMed:: 38087345

447.

Cepharanthine, a regulator of keap1-Nrf2, inhibits gastric cancer growth through oxidative stress and energy metabolism pathway.

Cepharanthine (CEP) derived from Stephania Cephalantha Hayata inhibits gastric cancer cell growth by inducing apoptosis and cell cycle arrest. It also regulates oxidative stress and alters energy metabolism, suggesting potential for gastric cancer treatment.

Cancer Gastroenterology Immunology Stephania cephalantha

Lu YY et al (2023).; Cell Death Discov.
DOI:: 10.1038/s41420-023-01752-z
PubMed:: 38086844

448.

Caragana sinica (Buc'hoz) Rehd. (jin ji er) polysaccharide regulates the immune function and intestinal microbiota of cyclophosphamide (CTX) induced immunosuppressed mice.

Gastroenterology Caragana sinica

Zhang Y et al (2024).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2023.117551
PubMed:: 38081398