Novel insights into enzymes inhibitory responses and metabolomic profile of supercritical fluid extract from chestnut shells upon intestinal permeability.

Chestnut shell extract has potential health benefits. It showed neuroprotective, hypoglycemic, and hypolipidemic properties by inhibiting certain enzymes. Phenolic compounds in the extract can be absorbed by the intestines and reach target sites.

Pinto D et al (2024).

Food Res Int.

DOI:

10.1016/j.foodres.2023.113807

PubMed:

38129012

Identification of EDNRA as the Key Biomarker for Hypercholesterolemia and Colorectal Cancer.

Han K et al (2024).

Tohoku J Exp Med.

DOI:

10.1620/tjem.2023.J101

PubMed:

38123303

Gastric acid-responsive deformable sodium alginate/Bletilla striata polysaccharide in situ gel for the protection and treatment of alcohol-induced peptic ulcers.

Fan Y et al (2023).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2023.128815

PubMed:

38114010

Bioactives and metabolites of Tetrastigma hemsleyanum root extract alleviate DSS-induced ulcerative colitis by targeting the SYK protein in the B cell receptor signaling pathway.

Feng Z, Ye W and Feng L (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117563

PubMed:

38104876

Phytochemically analysed extract of Ageratina adenophora (Sprengel) R.M.King & H. Rob. initiates caspase 3-dependant apoptosis in colorectal cancer cell: A synergistic approach with chemotherapeutic drugs.

Ageratina adenophora has been used in traditional medicine globally for various therapeutic purposes. It treats cancer, pain, fever, infections, and digestive issues. The plant is utilized by different ethnic groups in India, Portugal, and Nigeria.

Chanu KD et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117591

PubMed:

38104872

Anise (Pimpinella anisum L.) attenuates azoxymethane-induced colorectal cancer by antioxidant, anti-inflammatory, and anti-apoptotic pathways in rats.

The study investigated the toxic effect and chemoprotective potential of Pimpinella anisum L. seeds (PAS) against colon cancer. Results suggest that PAS at 400 mg/kg can inhibit aberrant crypto foci incidence and decrease oxidative stress, making it a potential additive for colorectal cancer pharmaceuticals.

Almaimani G et al (2023).

Environ Sci Pollut Res Int.

DOI:

10.1007/s11356-023-31349-z

PubMed:

38103135

Mechanisms of Actinidia chinensis Planch in treating colon cancer based on the integration of network pharmacology, molecular docking, and experimental verification.

The study used a combination of methods to investigate the effects and mechanisms of Actinidia chinensis Planch (ACP) as an anticancer herbal medicine for colon cancer. The findings could provide valuable insights for potential treatments.

Chen JF et al (2023).

Hereditas.

DOI:

10.1186/s41065-023-00303-x

PubMed:

38102686

Metagenomic sequencing revealed the regulative effect of Danshen and Honghua herb pair on the gut microbiota in rats with myocardial ischemia injury.

DHHP, a Chinese herb pair, relieves myocardial ischemia in rats by regulating gut microbiota. It improves diversity and increases beneficial bacteria while reducing harmful bacteria, offering potential for MI treatment.

Du SB et al (2024).

FEMS Microbiol Lett.

DOI:

10.1093/femsle/fnad133

PubMed:

38100390