Gastroenterology Studies

Artesunate alleviates intestinal ischemia/reperfusion induced acute lung injury via up-regulating AKT and HO-1 signal pathway in mice.

Artesunate, extracted from Artemisia annua, reduces intestinal ischemia/reperfusion (II/R) induced lung injury in mice by targeting oxidative stress, inflammation, and apoptosis via AKT and HO-1 activation. Potential therapeutic candidate for II/R induced acute lung injury.

Ji T et al (2023).
Int Immunopharmacol.
PubMed:
37441813

Garlic essential oil ameliorates depression-like behaviors in unpredictable chronic mild stress by modulating the brain NLRP3 inflammasome pathway and influencing the gut barrier and microbiota.

Garlic essential oil reduces dopamine/serotonin turnover rates, reverses depression in rats, inhibits inflammation, and promotes intestinal barrier function, potentially influencing depression-like behavior.

Huang YJ et al (2023).
Food Funct.
PubMed:
37435927