Anti-bacterial diarrhea effect and action mechanism of Portulaca oleracea L. water extract based on the regulation of gut microbiota and fecal metabolism.

He Y et al (2023).

J Sci Food Agric.

DOI:

10.1002/jsfa.12810

PubMed:

37357594

Mushroom polysaccharides from Grifola frondosa (Dicks.) Gray and Inonotus obliquus (Fr.) Pilat ameliorated dextran sulfate sodium-induced colitis in mice by global modulation of systemic metabolism and the gut microbiota.

Sun R et al (2023).

Front Pharmacol.

DOI:

10.3389/fphar.2023.1172963

PubMed:

37351508

Phytochemical analysis of Origanum majorana L. extract and investigation of its antioxidant, anti-inflammatory and immunomodulatory effects against experimentally induced colitis downregulating Th17 cells.

Taha M et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.116826

PubMed:

37348796

The colonic metabolism differences of main alkaloids in normal and colitis mice treated with Coptis chinensis Franch. and Sophora flavescens Ait. herbal pair using liquid chromatography-high resolution mass spectrometry method combined with chemometrics.

Li Q et al (2023).

J Sep Sci.

DOI:

10.1002/jssc.202300094

PubMed:

37339806

Investigating the effects of conventional and unconventional edible parts of red beet (Beta vulgaris L.) on target bacterial groups and metabolic activity of human colonic microbiota to produce novel and sustainable prebiotic ingredients.

de Oliveira SPA et al (2023).

Food Res Int.

DOI:

10.1016/j.foodres.2023.112998

PubMed:

37330844

Network pharmacology and molecular docking-based identification of drug candidates and key targets of Allium sativum for colorectal cancer treatment.

Scientists are exploring alternative treatments for colorectal cancer (CRC) due to the limitations of current chemotherapeutics. In this study, researchers investigated the potential anti-CRC effects of a medicinal plant, (). They analyzed the plant's bioactive compounds and identified key targets for CRC treatment. Gene set enrichment analysis revealed the biological processes and pathways that could potentially be restored in CRC. Molecular docking studies identified beta-sitosterol and alpha-bisabolene as compounds with the highest binding affinity for the key targets. Further experimental studies are needed to validate these findings. This research has the potential to contribute to the development of more effective and targeted CRC treatments.

Olukunle OF, Omoboyede V and Chukwuemeka PO (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2023.2220823

PubMed:

37325859

Investigating the modulatory effects of Moringa oleifera on the gut microbiota of chicken model through metagenomic approach.

Soundararajan S et al (2023).

Front Vet Sci.

DOI:

10.3389/fvets.2023.1153769

PubMed:

37323848

Extra virgin coconut oil (Cocos nucifera L.) intake shows neurobehavioural and intestinal health effects in obesity-induced rats.

Researchers studied the effects of E-VCO on obese rats. E-VCO reduced energy intake and body weight gain, showed antidepressant effects, and improved gut health. It may have potential for treating obesity-related comorbidities.

Araújo de Vasconcelos MH et al (2023).

Food Funct.

DOI:

10.1039/d3fo00850a

PubMed:

37318515