Immunology Studies

Targeted/untargeted metabolomics and antioxidant properties distinguish Citrus reticulata 'Chachi' from Citrus reticulata Blanco.

Researchers compared phenolic compounds and metabolites in different dried citrus peel species. Citrus reticulata Blanco had more total phenolic compounds and higher antioxidant activity compared to Citrus reticulata 'Chachi'. This study supports the high-value use of citrus peels.

Wang X et al (2024).
Food Chem.
PubMed:
39241684

Schisandra chinensis lignans improve insulin resistance by targeting TLR4 and activating IRS-1/PI3K/AKT and NF-κB signaling pathways.

Schisandra chinensis compounds 2 and 4 improve insulin resistance by targeting TLR4, modulating NF-κB and IRS-1/PI3K/AKT pathways, offering potential as T2DM treatments.

Zhao SL et al (2024).
Int Immunopharmacol.
PubMed:
39241520

Ocotillol-Type Pseudoginsenoside-F11 Alleviates Lipopolysaccharide-Induced Acute Kidney Injury through Regulation of Macrophage Function by Suppressing the NF-κB/NLRP3/IL-1β Signaling Pathway.

- AKI involves kidney function decline due to inflammation - PF11 from plant modulates macrophage function - Protects kidney cells and reduces inflammation in mouse model - Potential treatment for AKI by regulating macrophages

Wang Y et al (2024).
J Agric Food Chem.
PubMed:
39239930

Study on chemical constituents and antioxidant activities of Dianthus caryophyllus L.

Study evaluated antioxidant and antitumor properties of carnation plant extracts using metabolomics. Important for potential medicinal and ornamental value.

Wang M et al (2024).
Front Plant Sci.
PubMed:
39239204

Terminalia bellirica (Gaertn.) Roxb. extracts reshape the perifollicular microenvironment and regulate the MAPK pathway for androgenetic alopecia treatment.

Researchers studied the medicinal effects of Terminalia bellirica on male pattern baldness. TBR has multiple pharmacological activities and could potentially be used for AGA treatment.

Xiang H et al (2024).
J Ethnopharmacol.
PubMed:
39236776

Phenolic Compound Profiles, Antioxidant and Cytoprotective Activity of  Elaeagnus conferta Roxb. Fruit.

Three varieties of Elaeagnus conferta fruit from China were found to have high levels of antioxidants and protective effects on injured human cells. This suggests they could be useful for food industries.

Lu J et al (2024).
Chem Biodivers.
PubMed:
39235431

Antioxidant, anti-inflammatory and antibacterial activities of methanol extract and essential oil of two varieties of Citrus sinensis L. in Iran.

Study on antioxidant, anti-inflammatory, antifungal, antibacterial properties of two varieties of Iranian oranges. Northern orange skin had highest phenol and flavonoid content, antioxidant activity, anti-inflammatory effects, and positive impact on Gram-positive bacteria.

Bahramikia S, Habibi S and Shirzadi N (2024).
Nat Prod Res.
PubMed:
39234994

Hepatic changes following a high-fat diet: effects of Cornus mas and gold nanoparticles phytoreduced with Cornus mas on oxidative stress, inflammation, and histological damage.

"Study found HFD causes liver injury, CM and GNPsCM can protect against oxidative stress and inflammation. Important for potential treatment/prevention of liver damage from high fat diets."

Zugravu DD et al (2024).
Med Pharm Rep.
PubMed:
39234459