CKD-497 inhibits NF-kB signaling and ameliorates inflammation and pulmonary fibrosis in ovalbumin-induced asthma and particulate matter-induced airway inflammatory diseases.

CKD-497, derived from rhizome and fruits, reduces inflammation and mucus production in asthma and pollution-induced lung inflammation. It inhibits proinflammatory cytokines and NF-kB pathway, potentially protecting against respiratory diseases.

Kim H et al (2024).

Front Pharmacol.

DOI:

10.3389/fphar.2024.1428567

PubMed:

39170711

Phytochemical fingerprint revealing antibacterial and antioxidant activities of endemic banana cultivars in Southeast Asia.

Researchers analyzed bioactive compounds in banana peels to differentiate cultivars, identified key metabolites like rutin, chlorogenic acid, and gentisic acid, and showed their antioxidant and antibacterial properties. Results provide a reliable method for banana cultivar discrimination.

Ee LY et al (2024).

Heliyon.

DOI:

10.1016/j.heliyon.2024.e35139

PubMed:

39170182

Multi-target anti-diabetic styrylpyrones from Phellinus igniarius: Inhibition of α-glucosidase, protein glycation, and oxidative stress.

Phellinus igniarius SY489 extract contains potent α-glucosidase inhibitors, including novel compounds, with potential as anti-diabetic drugs. Study suggests they interact with enzyme via mixed-type mechanism for promising drug development.

Yu G et al (2024).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2024.134854

PubMed:

39168223

Lettuce (Lactuca sativa L.) alters its metabolite accumulation to cope with CuO nanoparticles by promoting antioxidant production and carbon metabolism.

Xu W et al (2024).

Environ Geochem Health.

DOI:

10.1007/s10653-024-02160-7

PubMed:

39167279

Antioxidant activities, dietary nutrients, and yield potential of bitter gourd (Momordica charantia L.) lines in diverse growing environments.

Jat GS et al (2024).

Front Nutr.

DOI:

10.3389/fnut.2024.1393476

PubMed:

39166126

Nanoparticle Encapsulation of the Hexane Fraction of Cyperus Rotundus Extract for Enhanced Antioxidant and Anti-Inflammatory Activities in vitro.

Kim C et al (2024).

Int J Nanomedicine.

DOI:

10.2147/IJN.S452636

PubMed:

39165772

Comprehensive phytochemical profiling of Phyllanthus emblica L. flowers on UHPLC/MS quadrupole time of flight, HPTLC, HPLC, and NMR analytical platforms reveals functional metabolites with potent anti-inflammatory effects in human (THP-1) macrophages.

Balkrishna A et al (2024).

Phytochem Anal.

DOI:

10.1002/pca.3433

PubMed:

39160136

Neolignans and Diarylnonanoid Derivatives with Anti-inflammatory Activity from Myristica fragrans Houtt. Seeds.

Le TT et al (2024).

ACS Omega.

DOI:

10.1021/acsomega.4c05649

PubMed:

39157106