Immunology Studies

Anticancer, antimicrobial and antioxidant activity of CuO-ZnO bimetallic nanoparticles: green synthesised from Eryngium foetidum leaf extract.

E. foetidum leaf extract was used to synthesize CuO-ZnO nanoparticles with potential anti-cancer, antimicrobial, and antioxidant properties. Results show promising cytotoxic effects on breast cancer cells and potent antimicrobial activity against various strains.

Daimari J and Deka AK (2024).
Sci Rep.
PubMed:
39174638

Vincamine exerts hepato-protective activity during colon ligation puncture-induced sepsis by modulating oxidative stress, apoptosis, and TNFα/Nrf-2/Keap-1 signaling pathways.

Vincamine protects the liver during sepsis by reducing liver enzymes, oxidative stress, inflammation, and apoptosis. It modulates key pathways to improve liver function.

Alaaeldin R et al (2024).
Sci Rep.
PubMed:
39174578

The phthalide compound tokinolide B from Angelica sinensis exerts anti-inflammatory effects through Nur77 binding.

Nur77 controls inflammation and is a potential target for treating inflammatory diseases. Angelica sinensis contains compounds that reduce inflammation. Important for developing anti-inflammatory therapies.

Xia Y et al (2024).
Phytomedicine.
PubMed:
39173278

Antidepressant-like and antioxidant effects of Morus nigra L. in rats subjected to the unpredictable chronic mild stress model.

Study shows Morus nigra leaf extract reduces depression-like behavior in stressed rats, possibly through antioxidant effects. Potential new treatment for depression.

Merida BF et al (2024).
Nat Prod Res.
PubMed:
39172975

Forsythiaside A ameliorates bleomycin-induced pulmonary fibrosis by inhibiting oxidative stress and apoptosis.

FA, from Forsythia plant, shows anti-inflammatory, antioxidant, and antiviral properties. It may help treat pulmonary fibrosis (PF), a serious disease with high morbidity and mortality.

Yang F et al (2024).
Immun Inflamm Dis.
PubMed:
39172055

Exploration of Pharmacological Mechanism of Cinnamomum tamala Essential Oil in Treating Inflammation based on Network Pharmacology, Molecular Modelling, and Experimental Validation.

Scientists studied Cinnamomum tamala for its anti-inflammatory properties. They found that Indian Bay leaf essential oil can reduce inflammation, but more research is needed to understand how it works.

Mohanty D et al (2024).
Curr Pharm Des.
PubMed:
39171467

Exploring sesquiterpene lactone as a dual therapeutic agent for diabetes and oxidative stress: insights into PI3K/AKT modulation.

Artemisinin shows potential for anti-diabetic and antioxidant effects by targeting the PI3K/AKT pathway. It inhibits enzymes related to hyperglycaemia and exhibits antioxidant properties without toxicity in zebrafish models. This suggests a promising therapy for diabetes and oxidative stress.

Velumani K et al (2024).
3 Biotech.
PubMed:
39170770