Immunology Studies

Correction to: Ginkgo biloba Extract 50 (GBE50) Exerts Antifibrotic and Antioxidant Effects on Pulmonary Fibrosis in Mice by Regulating Nrf2 and TGF-β1/Smad Pathways.

Liang W et al (2024).
Appl Biochem Biotechnol.
PubMed:
38421573

Polygalacic acid attenuates cognitive impairment by regulating inflammation through PPARγ/NF-κB signaling pathway.

Researchers studied how polygalacic acid from Polygala tenuifolia treats Alzheimer's disease. Understanding its mechanism can lead to new treatments for AD.

Zhao T and Jia J (2024).
CNS Neurosci Ther.
PubMed:
38421141

Effect of faba bean Vicia faba L. water/alcohol extract on growth performance, antioxidant capacity, textural properties, and collagen deposition in the swim bladder of juvenile Nibea coibor.

Researchers studied the effects of faba bean extract on Nibea coibor fish. 1.25% water extract improved growth, texture, and antioxidant capacity, while alcohol extract decreased growth. Water extract may enhance swim bladder quality. Useful for formulating diets for marine fish.

Guo H et al (2024).
Fish Physiol Biochem.
PubMed:
38418771

Asiaticasics A-O, structurally intriguing coumarins from Toddalia asiatica with potential inflammatory inhibitory activity.

T. asiatica yielded new prenylated coumarins (asiaticasics A-O), showing anti-inflammatory activity, particularly compound 12. Compound 12 may reduce pyroptosis by inhibiting NLRP3 inflammasome. Morphological observation supported bioactivity evaluation.

Song SC et al (2024).
Phytochemistry.
PubMed:
38417721

Modulation of macrophages by a phillyrin-loaded thermosensitive hydrogel promotes skin wound healing in mice.

Researchers studied a new treatment combining PF-127 and phillyrin to enhance wound healing by modulating macrophages. This has potential for treating traumatic skin injuries.

Huang C et al (2024).
Cytokine.
PubMed:
38417214

Immunomodulatory Role of Plants and Their Constituents on the Management of Metabolic Disorders: An Evidence-Based Review.

Plant-derived bioactive compounds show promise in improving metabolic and immune functions in patients with metabolic disorders. This review highlights the therapeutic potential of phytochemical formulations in alleviating conditions like obesity and diabetes. Further research and clinical trials are needed for validation.

Febriyanti RM, Levita J and Diantini A (2024).
Drug Des Devel Ther.
PubMed:
38415194

In vitro antimicrobial and antioxidant activities, essential oil composition, and in silico molecular modeling analysis of secondary metabolites from roots of Verbascum sinaiticum.

Researchers identified compounds in plant with antimicrobial and antioxidant properties. Root extracts showed potential against bacteria and free radicals. Further investigation recommended for medicinal use.

Tegegn G et al (2024).
Z Naturforsch C J Biosci.
PubMed:
38414256

Inhibition of IL-17 signaling in macrophages underlies the anti-arthritic effects of halofuginone hydrobromide: Network pharmacology, molecular docking, and experimental validation.

HF, derived from Chinese herb, shows promise in treating RA with anti-inflammatory effects. Further research needed to understand how HF works to benefit RA patients.

Zhu J et al (2024).
BMC Complement Med Ther.
PubMed:
38413973