Discovery of ent-labdane derivatives from Andrographis paniculata and their anti-inflammatory activity.

Scientists discovered andropanilide D as a potential anti-inflammatory treatment after testing compounds from Andrographis paniculata, suggesting its superior activity compared to dexamethasone and andrographolide.

Yu Y et al (2024).

Phytochemistry.

DOI:

10.1016/j.phytochem.2024.113986

PubMed:

38219853

Homeopathic preparation of Allium sativum abrogates OxLDL mediated atherogenic events in macrophages: An invitro and in silico approach.

Researchers explored the mechanism by which a homeopathic preparation of Allium sativum (garlic) counteracts the formation of foam cells caused by oxidized LDL (OxLDL), a major contributor to atherosclerosis. Understanding this mechanism could lead to potential therapeutic applications.

Mohan T et al (2024).

J Ayurveda Integr Med.

DOI:

10.1016/j.jaim.2023.100850

PubMed:

38219436

The anti-inflammatory and anti-apoptotic effects of Achillea millefolium L. extracts on Clostridioides difficile ribotype 001 in human intestinal epithelial cells.

Researchers investigated the effects of Achillea millefolium extracts on the growth of C. difficile and its inflammatory and apoptosis-inducing properties. These extracts show potential as alternative medicines against CDI, a common healthcare-acquired infection.

Raeisi H et al (2024).

BMC Complement Med Ther.

DOI:

10.1186/s12906-024-04335-2

PubMed:

38218845

Antipyretic effect of inhaled Tetrastigma hemsleyanum polysaccharide on substance and energy metabolism in yeast-induced pyrexia mice via TLR4/NF-κb signaling pathway.

Tetrastigma hemsleyanum is a useful plant for treating severe infectious diseases, but we don't know how it works. Understanding its mechanism could lead to better treatments.

Fu S et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.117732

PubMed:

38218501

Study on the chronic inflammatory injury caused by Ageratina adenophora on goat liver using metabolomics.

Study investigated inflammation and liver metabolism changes caused by A. adenophora ingestion in goats. Results show altered metabolites and pathways related to inflammation, along with liver injury and histopathological changes. Important for understanding A. adenophora hepatotoxicity and further research on liver metabolite changes.

Shao C et al (2024).

Toxicon.

DOI:

10.1016/j.toxicon.2024.107610

PubMed:

38218385

A novel polysaccharide isolated from Coriolus versicolor polarizes M2 macrophages into an M1 phenotype and reversesits immunosuppressive effect on tumor microenvironment.

Bi S et al (2024).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2024.129352

PubMed:

38218293

Discovery of bi-4-methoxycarbonyl-2-quinolone and evaluation of its anti-inflammatory and anti-cancer activity in vitro.

A new alkaloid compound with anti-inflammatory and anti-cancer properties was discovered, along with six known alkaloids, holding promise for potential therapeutic applications in inflammation and cancer treatment.

Wang W et al (2024).

Nat Prod Res.

DOI:

10.1080/14786419.2024.2303606

PubMed:

38217490

Two novel alkaloids from Portulaca oleracea L. and their anti-inflammatory bioactivities.

Two new alkaloids, Oleracrylimide D and Oleracrylimide E, were discovered in L. Their structures were identified using spectroscopic methods, and their anti-inflammatory properties were investigated using ELISA.

Wang C et al (2024).

Nat Prod Res.

DOI:

10.1080/14786419.2024.2303597

PubMed:

38217487