Immunology Studies

Akebia saponin D attenuates allergic airway inflammation through AMPK activation.

Akebia saponin D (ASD), extracted from Dipsacus asper Wall, inhibits inflammation in lung cells and mice through AMPK activation, suggesting ASD as a potential treatment for allergic airway inflammation.

Xuan L et al (2024).
J Nat Med.
PubMed:
38175326

Involvement of oxidative stress in localization of bacterial spot infection in pepper plants.

In this study, researchers focused on the pathogen Pseudomonas syringae, which causes bacterial spot disease in pepper plants. They found that the plants limit the spread of the pathogen and activate antioxidant defenses. This co-evolution between the plant and pathogen allows both to survive.

Brankova L et al (2024).
J Biosci.
PubMed:
38173312

Baicalin Induces Gastric Cancer Cell Pyroptosis through the NF-κB-NLRP3 Signaling Axis.

Baicalein, a component in traditional Chinese medicine, induces pyroptosis in gastric cancer cells through the NF-κB-NLRP3 signaling axis. This could be an effective and novel therapeutic approach for treating gastric cancer, providing hope for improved outcomes.

Liu J et al (2024).
J Cancer.
PubMed:
38169542

Evening primrose oil enriched with gamma linolenic acid and D/L-alpha tocopherol acetate attenuated carbon tetrachloride-induced hepatic injury model in male rats via TNF-α, IL-1β, and IL-6 pathway.

Gad El-Hak HN, Kishk SM and Abdelrazek HMA (2024).
Toxicol Mech Methods.
PubMed:
38166523