Antioxidant Potential of Ethiopian Medicinal Plants and Their Phytochemicals: A Review of Pharmacological Evaluation.

This study explores the use of antioxidant compounds from Ethiopian medicinal plants to protect cells from free radical damage, potentially aiding in the prevention and treatment of diseases like cancer and central nervous system damage. Further research is recommended.

Nigussie G et al (2023).

Evid Based Complement Alternat Med.

DOI:

10.1155/2023/1901529

PubMed:

37868204

A comparative analysis of phytochemicals, metal ions, volatile metabolites in heart wood, stem bark and leaves of Salix alba L. along with invitro antioxidant, antacid, antimicrobial activities for sake of environment conservation by substitution of stem bark with leaf.

Salix alba L. leaves are abundant in micronutrients, essential metals, possess strong antibacterial activity and higher antacid activity compared to stem bark and heartwood.

Gandhi Y et al (2023).

Chem Biodivers.

DOI:

10.1002/cbdv.202301234

PubMed:

37867394

Arctium lappa L. root polysaccharides ameliorate CCl(4)-induced acute liver injury by suppressing oxidative stress, inflammation and apoptosis.

Xiang W et al (2023).

Nat Prod Res.

DOI:

10.1080/14786419.2023.2272287

PubMed:

37867310

Shenlian extract improves atherosclerosis by relieving adventitial inflammation.

Han S et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117339

PubMed:

37866468

Puerarin alleviates hyperosmotic stress-induced oxidative stress, inflammation, apoptosis and barrier damage of human corneal epithelial cells by targeting SIRT1/NLRP3 signaling.

Dong Y, Ding YY and Gao WP (2024).

Toxicol In Vitro.

DOI:

10.1016/j.tiv.2023.105722

PubMed:

37865300

Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.

Mai Men Dong decoction (MMDD), a traditional Chinese medicine, contains herbs known for treating respiratory conditions. Studying MMDD can enhance understanding and development of ethnopharmacology.

Shuangshuang HE et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117308

PubMed:

37865276

Attenuation of CFA-induced arthritis through regulation of inflammatory cytokines and antioxidant mechanisms by Solanum nigrum L. leaves extracts.

The study evaluated the anti-arthritic effects of Solanum nigrum L. extracts. Results showed significant pain relief and reduction in inflammation. Extracts regulated inflammatory markers and improved oxidative stress, suggesting potential in treating arthritis.

Gul B et al (2023).

Inflammopharmacology.

DOI:

10.1007/s10787-023-01357-z

PubMed:

37864683

A high throughput method for detection of cyclooxygenase-2 enzyme inhibitors by effect-directed analysis applying high performance thin layer chromatography-bioassay-mass spectrometry.

Scientists developed a method to detect bioactive molecules that inhibit the COX-2 enzyme using a combination of bioassay, chromatography, and mass spectrometry. They optimized the conditions and used it to identify COX-2 inhibitors in Chiloe's giant garlic extract.

Oyarzún P et al (2023).

J Chromatogr A.

DOI:

10.1016/j.chroma.2023.464426

PubMed:

37862751