Immunology Studies

Effect of dietary onion (Allium cepa L.) powder as an antioxidant on semen quality, blood biochemicals, and reproductive parameters, as well as immunological variables of rabbit bucks under severe heat stress.

This study found that feeding rabbit bucks onion powder improved semen quality, red blood cell levels, hormone levels, and antioxidant levels, counteracting the negative effects of heat stress. This suggests that onion powder could benefit rabbit health and reproduction. (42 words)

El-Gindy YM et al (2023).
Trop Anim Health Prod.
PubMed:
37882945

The JAK/STAT/NF-κB signaling pathway can be regulated by rosemary essential oil, thereby providing a potential treatment for DNCB-induced in mice.

This study explores how rosemary essential oil helps treat atopic dermatitis, offering insights for potential therapeutic applications in managing the condition.

Li J et al (2023).
Biomed Pharmacother.
PubMed:
37879216

Inhibiting NF-κB-S100A11 signaling and targeting S100A11 for anticancer effects of demethylzeylasteral in human colon cancer.

Demethylzeylasteral, a natural compound derived from Tripterygium wilfordii, has shown potent anti-colon cancer activity. This study identifies S100A11 as a target protein and NF-κB as a regulator of S100A11 expression, highlighting the potential of demethylzeylasteral for anti-tumor therapy.

Li W et al (2023).
Biomed Pharmacother.
PubMed:
37879212

The ability of supercritical CO(2) carrot and pumpkin extracts to counteract inflammation and oxidative stress in RAW 264.7 macrophages stimulated with LPS or MDA-MB-231 cell-conditioned media.

Frattaruolo L et al (2023).
Food Funct.
PubMed:
37870074

Toxicological Assessment and Anti-diabetic Effects of Combined Extract of Chirata, Fenugreek and Sesame on Regulating TNF-α, TGF-β and Oxidative Stress in Streptozotocin Induced Diabetic Rats.

Researchers investigated the potential of Swertia chirayita, Trigonella foenum-gracum, and Sesamum indicum in treating diabetes. Understanding the role of innate immunity and inflammation in diabetes-related microvascular problems is crucial.

Shivam and Gupta AK (2023).
Curr Drug Discov Technol.
PubMed:
37870057

Phytochemical profiling and anti-inflammatory, analgesic activity of Ficus religiosa L. and molecular docking study against iNOS, TNF-α enzyme.

The study investigated the anti-inflammatory and analgesic properties of Ficus religiosa bark extract and the component quercetin. Both showed significant reduction in paw volume and pain symptoms, suggesting their potential use in treating pain and inflammation.

Ahmad S et al (2023).
Pak J Pharm Sci.
PubMed:
37869923