Immunology Studies

Solamargine induces apoptosis of human renal carcinoma cells via downregulating phosphorylated STAT3 expression.

Solamargine (SM) inhibits tumor cell proliferation and induces apoptosis in human renal carcinoma cells. It downregulates p-STAT3 expression and activates caspase proteins, promoting cell death. SM also inhibits tumor growth in mice without causing organ toxicity.

Huang S et al (2023).
Oncol Lett.
PubMed:
37854861

Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review.

Hyperoside is a natural compound found in many plants. It has many beneficial effects, including anti-inflammatory, antidepressant, and antioxidant properties. This review provides a summary of its characteristics, potential uses, and effectiveness, helping in the development of new drugs and maximizing its potential.

Wang K et al (2023).
J Inflamm Res.
PubMed:
37854313

Optimization of ultrasound-assisted extraction based on response surface methodology using HPLC-DAD for the analysis of red clover (Trifolium pretense L.) isoflavones and its anti-inflammatory activities on LPS-induced 3D4/2 cell.

Researchers found that red clover has several beneficial effects, including anti-inflammatory, antioxidant, and cardiovascular disease prevention. The current method for testing its components is inadequate, and little is known about its regulatory effect on inflammation in porcine macrophages. Further research is needed.

Luo Z et al (2023).
Front Vet Sci.
PubMed:
37854095

Secoiridoid glycosides from the fruits of Ligustrum lucidum and their in vitro anti-inflammatory activity.

Researchers discovered seven new secoiridoid glycosides from the fruits of Ligustrum lucidum. These compounds have unique structures and show potential anti-inflammatory properties.

Peng YS et al (2023).
Fitoterapia.
PubMed:
37852389

Unveiling the antibacterial and antioxidant potential of Hedera helix leaf extracts: recent findings.

L. leaf extract exhibits antioxidant and antibacterial properties with potential for treating infections, requiring further study to identify active compounds and mechanisms.

Qabaha K et al (2023).
Can J Physiol Pharmacol.
PubMed:
37850568

Peppermint as a promising treatment agent in inflammatory conditions: A comprehensive systematic review of literature.

Goudarzi MA, Radfar M and Goudarzi Z (2024).
Phytother Res.
PubMed:
37850332

Impact of a retrograded starch ingredient obtained from Negro Jamapa beans (Phaseolus vulgaris L. Negro Jamapa) on glucose metabolism and oxidative stress in induced diabetic lab rats model.

Retrograded starch from Negro Jamapa beans reduced digestible starch, improved glucose levels, reduced hyperglycemia, improved weight gain, and reduced insulin resistance in diabetic animals.

Diéguez TS et al (2023).
Int J Biol Macromol.
PubMed:
37844824