Immunology Studies

Exploring the therapeutic potential of Prinsepia utilis Royle seed oil: A comprehensive study on chemical composition, physicochemical properties, anti-inflammatory, and analgesic activities.

Researchers studied the medicinal benefits of Prinsepia utilis (PU) Royle, a shrub from the Himalayan region used traditionally for treating conditions like pain and inflammation. Their findings may provide insights for potential therapeutic applications.

Chauhan K et al (2023).
J Ethnopharmacol.
PubMed:
37844743

Tubermycin B coated on Galactosylated Chitosan Nanoparticles synthesized by eco-friendly method ameliorates intracellular free radical production and reduces oxidative stress, reducing phosphorylation of IKKα/β/pIкBα/NF-кB pathway.

Binshaya AS et al (2023).
Eur Rev Med Pharmacol Sci.
PubMed:
37843350

The Efficacy of Topical Formulation Containing Ciplukan (Physalis angulata Linn.) in Modulating Interleukin-17 and Interferon Gamma Expression in Mice (Mus musculus) Psoriasis Model.

Researchers studied the potential of Linn. (Ciplukan) as an alternative topical therapy for psoriasis vulgaris. It possesses anti-inflammatory properties that could replace long-term use of corticosteroids with associated side effects.

Suwarsa O et al (2023).
J Exp Pharmacol.
PubMed:
37842316

Comparative analysis of the phenolic contents and antioxidant activities of different parts of two pomegranate (Punica granatum L.) Cultivars: 'Tunisia' and 'Qingpi'.

Study analyzes phenolic content & antioxidant activity in pomegranate parts. Petals contain highest polyphenols, placenta has highest flavonoids & punicalagin. Placenta is vital for punicalagin. Antioxidant activity highest in placenta.

Zhang H et al (2023).
Front Plant Sci.
PubMed:
37841630

The effect of Abelmoschus esculentus L. (Okra) extract supplementation on glycemic control, inflammation, kidney function, and expression of PPAR-α, PPAR-γ, TGF-β, and Nrf-2 genes in patients with diabetic nephropathy: A triple-blinded, randomized, placebo-controlled trial.

This study found that okra extract supplementation did not have significant effects on kidney function, glycemic control, inflammation, or gene expression in patients with diabetic nephropathy. The results suggest that okra extract may not be an effective treatment for DN.

Nikpayam O et al (2023).
Br J Nutr.
PubMed:
37840235

A neutral heteropolysaccharide from Halenia elliptica D. Don: Extraction, structural characterization, antioxidant and antiaging activities.

Researchers studied a polysaccharide (HEPN-1) from Halenia elliptica and found it has potential antioxidant properties. It improved enzyme activity, reduced oxidative stress, and enhanced learning and memory in mice. It also showed potential in preventing aging.

Zhou S et al (2023).
Carbohydr Polym.
PubMed:
37839842

Guaianolide-type sesquiterpene lactones from Achillea millefolium L. and their anti-inflammatory activity.

Seventeen new compounds, millefoliumines A-Q, were found in Achillea millefolium plants from Xinjiang, China. Millefoliumine G showed promise as an anti-inflammatory agent by reducing NO release and pro-inflammatory cytokine levels. Implications for drug development.

Li H et al (2023).
Phytochemistry.
PubMed:
37839587