Immunology Studies

Involvement of estrogen receptor activation in kaempferol-3-O-glucoside's protection against aging-related cognition impairment and microglial inflammation.

Kaempferol-3-O-glucoside (K-3-G), a flavonoid in Cuscuta Chinensis Lam., improved cognition and reduced inflammation in aging mice. It activated estrogen receptors (ERs) and inhibited microglial inflammation through ERs, suggesting it could be a therapeutic agent for cognitive decline.

Liu H et al (2023).
Exp Cell Res.
PubMed:
37926343

Macelignan prevents colorectal cancer metastasis by inhibiting M2 macrophage polarization.

Researchers investigated the effect of macelignan, a compound found in Myristica fragrans, on the polarization of tumor-associated macrophages in colorectal cancer metastasis. Understanding this interaction can potentially lead to new strategies for cancer treatment. (37 words)

Che N et al (2023).
Phytomedicine.
PubMed:
37925889