Immunology Studies

Improved antioxidant activities of spice require enrichment of distinct yet closely-related metabolic pathways.

The researchers used a reverse association strategy to identify target metabolic pathways for increased production of phytochemicals. They found enrichment of isoprenoids and fatty acids biosynthetic pathways, indicating a need for enrichment of specific metabolic pathways to achieve improved antioxidant effects in spices.

Gandhi S, Saha MR and Dey P (2023).
Heliyon.
PubMed:
37920519

Immune regulation and inflammation inhibition of Arctium lappa L. polysaccharides by TLR4/NF-κB signaling pathway in cells.

Scientists extracted and purified polysaccharides from burdock roots, which showed antioxidant and anti-inflammatory effects in cells. It has potential as a functional food or nutraceutical to improve the immune system and treat intestinal inflammation.

Zeng F et al (2023).
Int J Biol Macromol.
PubMed:
37918584

Inhalation of Spray-Dried Extract of Salvia rosmarinus Spenn Alleviates Lung Inflammatory, Oxidative, and Remodeling Changes in Asthmatic Rats.

Researchers investigated the effects of rosemary extract on airway inflammation in asthmatic rats. The extract showed anti-oxidative and anti-inflammatory properties, suggesting that it could be beneficial for treating respiratory conditions.

Rajizadeh MA et al (2023).
Pharmacology.
PubMed:
37918369

Effects of topping on rhizome, and analysis of chemical composition, antioxidant activity and α-amylase and α-glucosidase inhibition of the aerial parts in Polygonatum cyrtonema.

Topping the aerial part of Polygonatum cyrtonema increases rhizome yield and saponin content. The stem, leaves, and flowers have strong antioxidant and hypoglycemic activities, along with high polyphenol, flavonoid, protein, and amino acid content. This research suggests the potential for developing these parts for various applications.

Tang W, Chen Y and Guo F (2023).
PLoS One.
PubMed:
37917721

Extraction of Ampelopsis japonica polysaccharides using p-toluenesulfonic acid assisted n-butanol three-phase partitioning: Physicochemical, rheological characterization and antioxidant activity.

Scientists used an efficient method to extract polysaccharides from Ampelopsis japonica. They analyzed the composition, structure, and antioxidant properties of the polysaccharides. The results suggest that Ampelopsis japonica polysaccharides have potential as natural antioxidants in food and pharmaceutical industries.

Wu Y et al (2023).
Int J Biol Macromol.
PubMed:
37913878

Virgin Coconut Oil Alleviates Dextran Sulphate-Induced Inflammatory Bowel Disease and Modulates Inflammation and Immune Response in Mice.

The researchers studied the effects of virgin coconut oil on inflammatory bowel disease and immunosuppression in animals. Results suggest it has potential benefits due to its antioxidant, anti-inflammatory, and other properties.

Prabha S et al (2023).
J Am Nutr Assoc.
PubMed:
37905950

Assessment of the anti-inflammatory and analgesic effects of Opuntia ficus indica L. Cladodes extract.

The study evaluated the anti-inflammatory and analgesic properties of L. extract in rats and mice. Results showed it reduced pain and inflammation, and chemical analysis identified 20 compounds with therapeutic effects. The extract could be a promising, affordable natural remedy for pain and inflammation in small animals, but more research is needed.

Ammam A et al (2023).
Libyan J Med.
PubMed:
37905304