Immunology Studies

Production of Gypenoside XVII from Ginsenoside Rb1 by Enzymatic Transformation and Their Anti-Inflammatory Activity In Vitro and In Vivo.

Scientists cloned and expressed a gene encoding an enzyme that converts ginsenoside Rb1 into gypenoside XVII, a compound with improved anti-inflammatory activity. This method has potential for large-scale production of gypenoside XVII as a new anti-inflammatory drug.

Zhou K et al (2023).
Molecules.
PubMed:
37836844

Multi-Target Effect of Aloeresin-A against Bacterial and Host Inflammatory Targets Benefits Contact Lens-Related Keratitis: A Multi-Omics and Quantum Chemical Investigation.

Researchers identified aloeresin-A as a potential inhibitor for bacterial and host targets in contact lens-mediated microbial keratitis. It demonstrated strong binding energies and stable interactions, making it a promising candidate for inhibiting keratitis. Further research is needed for integration into lens care solutions.

Roshni J et al (2023).
Molecules.
PubMed:
37836798

Diversity, Antimicrobial, Antioxidant, and Anticancer Activity of Culturable Fungal Endophyte Communities in Cordia dichotoma.

Indian medicinal plant yields bioactive endophytic fungus, OP870014, with potent antimicrobial, antioxidant, and anticancer properties, introducing the possibility of using these fungi as a natural source of therapeutic compounds.

Sharma M et al (2023).
Molecules.
PubMed:
37836769

Methanol Extracts from Cirsium japonicum DC. var. australe Kitam. and Their Active Components Reduce Intracellular Oxidative Stress in Caenorhabditis elegans.

This study explored the antioxidative ability of different parts of DC. var. Kitam. plant. Leaf extracts showed the highest dry weight and all parts contained silychristin and taxifolin. Flower, leaf, and stem extracts reduced oxidative stress, indicating the potential health benefits and use as a silymarin source.

Yen PL et al (2023).
Molecules.
PubMed:
37836767

Chemical Composition of Litsea pungens Essential Oil and Its Potential Antioxidant and Antimicrobial Activities.

The study extracted essential oils from a plant with medicinal and edible properties. The oils showed antioxidant and antibacterial activities, making the plant a potential candidate for medicinal and edible purposes.

Chen T et al (2023).
Molecules.
PubMed:
37836677

Dandelion Polysaccharides Ameliorate High-Fat-Diet-Induced Atherosclerosis in Mice through Antioxidant and Anti-Inflammatory Capabilities.

Dandelion polysaccharides were found to reduce triglyceride levels, cholesterol levels, and atherosclerotic lesions in mice. They also increased collagen content and antioxidant enzyme activity, while reducing pro-inflammatory cytokines. Dandelion polysaccharides may be beneficial for treating atherosclerosis.

Zhou S et al (2023).
Nutrients.
PubMed:
37836404