Immunology Studies

Green synthesis of zinc and nickel dual-doped cerium oxide nanoparticles: antioxidant activity and cytotoxicity effects.

Dual-doped cerium oxide nanoparticles (CeO-NPs) were synthesized using zucchini peel extract. They showed increased size at higher temperatures and effectively killed cells at inhibitory concentrations. These nanoparticles also affected the enzymatic activity of SOD and CAT, intensifying CAT activity without affecting SOD activity.

Mahmoodi P et al (2023).
Bioprocess Biosyst Eng.
PubMed:
37700115

A new alkaloid from Portulaca oleracea L. with its anti-inflammatory activity.

Scientists discovered a new alkaloid, oleraisoindole B, from L. It showed anti-inflammatory activity at 5 μM. The structure was determined using NMR and UHPLC-ESI-Q-TOF/MS spectroscopic methods.

Yao J et al (2023).
Z Naturforsch C J Biosci.
PubMed:
37698627

Baicalin attenuated metabolic dysfunction-associated fatty liver disease by suppressing oxidative stress and inflammation via the p62-Keap1-Nrf2 signalling pathway in db/db mice.

Baicalin, found in Scutellaria baicalensis Georgi, shows promise in treating metabolic dysfunction-associated fatty liver disease (MAFLD). It reduces lipid accumulation, cirrhosis, and apoptosis in the liver by enhancing antioxidant enzymes through the p62-Keap1-Nrf2 pathway.

Liu WJ et al (2023).
Phytother Res.
PubMed:
37697721

Antioxidant activity and mineral content of Impatiens tinctoria A. Rich (Ensosila) tuber, an Ethiopian medicinal plant.

Impatiens tinctoria tuber extract contains antioxidants, minerals, and potential for cosmetic use due to its protective properties against skin damage.

Gidamo GH et al (2023).
Sci Rep.
PubMed:
37696977

Cold pressed Pinus halepensis Mill. seed oil for potential health applications: Analgesic, anti-inflammatory effects, and assessment of inflammatory mediators by RT-qPCR in skin wound healing.

The researchers investigated the medicinal properties of Pinus halepensis seed, which is commonly consumed in the Mediterranean region. It has been traditionally used to treat various diseases.

Ait Atmane S et al (2024).
J Ethnopharmacol.
PubMed:
37696441

Polysaccharides from Polygonatum cyrtonema Hua prevent post-traumatic stress disorder behaviors in mice: Mechanisms from the perspective of synaptic injury, oxidative stress, and neuroinflammation.

P. cyrtonema Hua is used in traditional Chinese medicine to treat depression syndrome. The study examines the effects of its active component, PSP, on PTSD and its mechanisms. Results are unknown.

Xie P et al (2023).
J Ethnopharmacol.
PubMed:
37696440

Iridoid- and flavonoid-enriched fractions of Cornus sanguinea and Cornus mas exert antioxidant and anti-inflammatory effects and inhibit key enzymes in the treatment of metabolic disorders.

Tenuta MC et al (2023).
Food Funct.
PubMed:
37694378

Phytochemical Characteristics and Anti-Inflammatory, Immunoregulatory, and Antioxidant Effects of Portulaca oleracea L.: A Comprehensive Review.

Purslane is a plant with antioxidant and anti-inflammatory properties. It contains various compounds that reduce inflammation, improve immune function, and combat oxidative stress. This makes it a potential treatment for inflammatory and immune diseases.

Ghorani V et al (2023).
Evid Based Complement Alternat Med.
PubMed:
37693918