Attenuation of CFA-induced chronic inflammation by a bicyclic monoterpene fenchone targeting inducible nitric oxide, prostaglandins, C-reactive protein and urea.

Fenchone, found in certain plants, has strong anti-inflammatory properties. In a rat model, it reduced pro-inflammatory markers and improved symptoms of chronic joint inflammation, suggesting therapeutic potential for inflammatory disorders.

Nawaz S et al (2023).

Inflammopharmacology.

DOI:

10.1007/s10787-023-01333-7

PubMed:

37689616

Phytochemicals and UHPLC-QTOF-HRMS characterisation of bioactives of butterfly pea (Clitoria ternatea L.) seeds and their antioxidant potentials.

The study found that Clitoria ternatea seeds have high nutrient content and contain bioactives such as rutin and sinapic acid. The seeds could be useful in the food and pharmaceutical industries.

Padmanabhan V, Kumar SS and Giridhar P (2023).

Food Chem.

DOI:

10.1016/j.foodchem.2023.137373

PubMed:

37688820

Development of innovative antioxidant food packaging systems based on natural extracts from food industry waste and Moringa oleifera leaves.

Barzan G et al (2024).

Food Chem.

DOI:

10.1016/j.foodchem.2023.137088

PubMed:

37688815

Anti-inflammatory compounds from the rhizome of Acorus calamus var. angustatus Besser and their mechanism.

Seven compounds were isolated from the rhizome of a medicinal plant. They showed anti-inflammatory activity by increasing GSH-PX and SOD levels and decreasing MDA, TNF-α, IL-1β, and IL-6 levels. Compound 4 had the strongest anti-inflammatory effect and may inhibit Beclin-1-dependent autophagy.

Huang L et al (2023).

Nat Prod Res.

DOI:

10.1080/14786419.2023.2255919

PubMed:

37688474

The Aqueous Extract of Brassica oleracea L. Exerts Phytotoxicity by Modulating H(2)O(2) and O(2)(-) Levels, Antioxidant Enzyme Activity and Phytohormone Levels.

Researchers demonstrated that extract can inhibit the growth of L.varruderale Kit. The extract reduced levels of harmful compounds in roots, increased antioxidant activity in shoots, and increased phytohormone content in seedlings, leading to weed suppression.

Wang Y et al (2023).

Plants (Basel).

DOI:

10.3390/plants12173086

PubMed:

37687333

Antioxidant Activity and Chemical Composition of Geranium Oil and Its Synergistic Potential against Pneumococci with Various Antibiotic Combinations.

Study finds combining L. essential oil with antibiotics improves effectiveness and enhances killing activity in macrophage cells, offering a potential immunotherapeutic strategy against infections and antibiotic resistance.

Dumlupinar B et al (2023).

Plants (Basel).

DOI:

10.3390/plants12173080

PubMed:

37687327

Effect of Plant Extracts Combinations on TNF-α, IL-6 and IL-10 Levels in Serum of Rats Exposed to Acute and Chronic Stress.

This study examines the effects of combined plant extracts rich in flavonoids on cytokine levels in stressed rats. The extracts, Antistress I and Antistress II, showed potential in reducing pro-inflammatory cytokines (TNF-α and IL-6) and increasing anti-inflammatory cytokine (IL-10) levels. The combinations were more effective than individual extracts.

Kandilarov I et al (2023).

Plants (Basel).

DOI:

10.3390/plants12173049

PubMed:

37687297

Exploring the Biomedical Applications of Biosynthesized Silver Nanoparticles Using Perilla frutescens Flavonoid Extract: Antibacterial, Antioxidant, and Cell Toxicity Properties against Colon Cancer Cells.

Biomimetic synthesis of silver nanoparticles (AgNPs) using a flavonoid extract as a reducer and capper. PFFE-AgNPs showed cytotoxic effects against cancer cells, inhibition of bacteria, and antioxidant activity. Promising potential for biomedical applications, but further research needed for safety and efficacy.

Hou T et al (2023).

Molecules.

DOI:

10.3390/molecules28176431

PubMed:

37687260