Chemical characterization, antioxidant and antidiabetic activities of a novel polyherbal formulation comprising of Hordeum vulgare, Elettaria cardamomum and Cicer arietinum extracts.

The researchers formulated poly-herbal granules (PHGs) using seeds of and to manage diabetes. The PHGs showed antioxidant and antidiabetic potential due to the presence of flavonoids and phenolic acid derivatives.

Iqbal R et al (2023).

Heliyon.

DOI:

10.1016/j.heliyon.2023.e19292

PubMed:

37662785

In vitro production of steroidal saponin, total phenols and antioxidant activity in callus suspension culture of Paris polyphylla Smith: an important Himalayan medicinal plant.

The study optimized the cultivation technique for callus suspension of the Smith (Melanthiaceae) plant. It found that 0.5 μM TDZ resulted in the maximum callus biomass, while 50 μM MeJA showed significant phenolic content and antioxidant activity. The research has commercial implications for the pharmaceutical and nutraceutical sectors.

Rawat JM et al (2023).

Front Plant Sci.

DOI:

10.3389/fpls.2023.1225612

PubMed:

37662142

A combination of isoliquiritigenin with Artemisia argyi and Ohwia caudata water extracts attenuates oxidative stress, inflammation, and apoptosis by modulating Nrf2/Ho-1 signaling pathways in SD rats with doxorubicin-induced acute cardiotoxicity.

The combination of Artemisia argyi and Ohwia caudata extracts with isoliquiritigenin can protect against doxorubicin-induced cardiac damage. It activates the AKT/PI3K signaling pathway and upregulates antioxidant markers, while inhibiting inflammatory response genes. Promising for cardiac hypertrophy and inflammatory disease treatment.

Yuan Hsieh DJ et al (2023).

Environ Toxicol.

DOI:

10.1002/tox.23936

PubMed:

37661764

Gastroprotective potential of red onion (Allium cepa L.) peel in ethanol-induced gastric injury in rats: Involvement of Nrf2/HO-1 and HMGB-1/NF-κB trajectories.

This study explores the use of onion (Allium cepa L.) for its anti-inflammatory and antioxidant properties in traditional medicine, particularly in treating gastric ulcers. Consider incorporating onion in your lab's research on natural remedies for various ailments.

Ali NB et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117115

PubMed:

37659760

Enhanced expression of RAGE/NADPH oxidase signaling pathway and increased level of oxidative stress in brains of rats with chronic fluorosis and the protective effects of blockers.

Ma YL et al (2023).

J Trace Elem Med Biol.

DOI:

10.1016/j.jtemb.2023.127288

PubMed:

37659123

Ameliorating effect of Citrus trifoliata L. fruits extract on motor incoordination, neurodegeneration and oxidative stress in Parkinson's disease model.

Researchers investigated the traditional use of Poncirus trifoliata (Trifoliate orange) in treating neurodegenerative disorders. The results showed the need for more scientific evidence to support its effectiveness. This information is important for making informed decisions in the lab.

Abdel-Kawy MA et al (2023).

Nutr Neurosci.

DOI:

10.1080/1028415X.2023.2253026

PubMed:

37658797

Anti-Inflammatory Effects and Macrophage Activation Induced by Bioavailable Cinnamon Polyphenols in Mice.

Song Y et al (2023).

Mol Nutr Food Res.

DOI:

10.1002/mnfr.202200768

PubMed:

37658489

Herbal melanin modulates PGE2 and IL-6 gastroprotective markers through COX-2 and TLR4 signaling in the gastric cancer cell line AGS.

The study found that a herbal melanin derived from Nigella sativa upregulated the TLR4 receptor, increased COX-2 expression, and promoted the secretion of PGE2 and IL-6 in AGS cells. This suggests that the melanin may have gastroprotective effects and potential benefits for gastric prevention and treatment.

El-Obeid A et al (2023).

BMC Complement Med Ther.

DOI:

10.1186/s12906-023-04124-3

PubMed:

37658354