Immunology Studies

The aqueous extract of Artemisia Absinthium L. stimulates HO-1/MT-1/Cyp450 signaling pathway via oxidative stress regulation induced by aluminium oxide nanoparticles (α and γ) animal model.

Karami E et al (2023).
BMC Complement Med Ther.
PubMed:
37670294

Effect of Field Trial on Silymarin Complex Composition and Antioxidant Assessment of Milk Thistle (Silybum marianum L. Gaertner).

Researchers conducted a trial to study the impact of growing conditions on milk thistle quality. They found that weather conditions and row spacing significantly influenced the yields of health-beneficial compounds. Highest yields were obtained in the 2021 growing season with a spacing of 37 cm.

Pluháčková H et al (2023).
Plant Foods Hum Nutr.
PubMed:
37668769

Phytochemical Constituents from the Seeds of Capsella bursa-pastoris and Their Antioxidant Activities.

Scientists investigated the seeds of a plant called Capsella bursa-pastoris and found a new organic acid and several known compounds. They tested the antioxidant capacities of these substances and found that some of them showed potential neuroprotective effects against oxidative damage in HT-22 cells.

Zhou TQ et al (2023).
Plant Foods Hum Nutr.
PubMed:
37668768

Olea europaea L. Leaf Extract Alleviates Fibrosis Progression and Oxidative Stress Induced by Bleomycin on a Murine Model of Lung Fibrosis.

Industrial leaf extract (OLE) reduced pulmonary fibrosis (PF) induced by bleomycin (BLM) in rats. OLE stabilized oxidative parameters, normalized enzyme activities, and reduced collagen accumulation, suggesting it has potential as a protective treatment against PF.

Bahri S et al (2023).
Dose Response.
PubMed:
37667683

Foliar application of chitosan-putrescine nanoparticles (CTS-Put NPs) alleviates cadmium toxicity in grapevine (Vitis vinifera L.) cv. Sultana: modulation of antioxidant and photosynthetic status.

Researchers found that a nano-conjugate of putrescine and chitosan improved the resistance of grapevines to cadmium stress, which could help protect crop productivity and human health.

Panahirad S et al (2023).
BMC Plant Biol.
PubMed:
37667189

Neuroprotection against Aluminum Chloride-Induced Hippocampus Damage in Albino Wistar Rats by Leucophyllum frutescens (Berl.) I.M. Johnst. Leaf Extracts: A Detailed Insight into Phytochemical Analysis and Antioxidant and Enzyme Inhibition Assays.

Scientists studied a new plant to see if it could be used to prevent and treat neurodegenerative diseases like Alzheimer's. Care because it could lead to new treatments.

Ahmad I et al (2023).
Front Biosci (Landmark Ed).
PubMed:
37664939

Bauhinia championii alleviates extracellular matrix degradation in IL-1β induced chondrocytes via miRNA-145-5p/TLR4/NF-κB axis.

The study investigated the effects of a herbal medicine, BCAE, on chondrocytes in osteoarthritis. BCAE promoted cell viability, reduced extracellular matrix degradation, and inhibited the TLR4/NF-κB signaling pathway, potentially protecting chondrocytes from degeneration.

Lin J et al (2023).
Heliyon.
PubMed:
37664703

Nephroprotective effects of Datura stramonium leaves against methotrexate nephrotoxicity via attenuation of oxidative stress-mediated inflammation and apoptosis in rats.

Researchers investigated whether a leaf extract could counteract the kidney-damaging side effects of the anticancer drug methotrexate in rats. This study is relevant for improving the clinical application of methotrexate in cancer treatments.

Alum EU et al (2023).
Avicenna J Phytomed.
PubMed:
37663387