Tinopanoids K-T, clerodane diterpenoids with anti-inflammatory activity from Tinospora crispa.

Zhu YL et al (2023).

Bioorg Chem.

DOI:

10.1016/j.bioorg.2023.106812

PubMed:

37651894

ScAREB4 promotes potato constitutive and acclimated freezing tolerance associated with enhancing trehalose synthesis and oxidative stress tolerance.

Liu T et al (2023).

Plant Cell Environ.

DOI:

10.1111/pce.14707

PubMed:

37651608

Assessing the potential of rosary pea (Abrus precatorius L.) derived aqueous seed extracts as anticancer agents and their phytoconstituents as COX-2 inhibitor: an in-vitro and in-silico approach.

L. is a medicinal remedy with diverse bioactivities. Aqueous seed extracts have high antioxidant, antiproliferative, antiangiogenic properties. They show potential as anticancer and antiangiogenic drugs.

Kaur A et al (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2023.2251053

PubMed:

37649393

Geniposide suppressed OX-LDL-induced osteoblast apoptosis by regulating the NRF2/NF-κB signaling pathway.

Scientists investigated the effect of geniposide, a natural compound from Eucommia ulmoides, on osteoporosis. Geniposide was found to protect against the development of osteoporosis induced by cholesterol accumulation. This research can contribute to the development of potential drugs for treating osteoporosis.

Xiao Y et al (2023).

J Orthop Surg Res.

DOI:

10.1186/s13018-023-04125-5

PubMed:

37649066

Egyptian mandarin peel oil's anti-scabies potential via downregulation-of-inflammatory/immune-cross-talk: GC-MS and PPI network studies.

The study found that Egyptian mandarin peel oil can effectively treat sarcoptic mange in rabbits. It identified key therapeutic targets and compounds in the oil that contribute to its scabicidal effect. This could provide a natural and cost-effective alternative treatment for the disease.

Elmaidomy AH et al (2023).

Sci Rep.

DOI:

10.1038/s41598-023-38390-5

PubMed:

37648727

The protective role of Achyranthes aspera extract against cisplatin-induced nephrotoxicity by alleviating oxidative stress, inflammation, and PANoptosis.

Study investigated the protective effects of Achyranthes aspera on renal dysfunction. Findings offer insights into its potential therapeutic benefits and could guide further research for developing new treatment options.

Lin SY et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117097

PubMed:

37648176

Hordeum vulgare ethanolic extract mitigates high salt-induced cerebellum damage via attenuation of oxidative stress, neuroinflammation, and neurochemical alterations in hypertensive rats.

High salt intake causes neurological damage in hypertensive rats. Barley extract reduces blood pressure, oxidative stress, inflammation, and restores neurotransmitter balance, suggesting it could be a treatment for high salt-induced hypertension and neurodegenerative diseases.

Ahmed-Farid OA et al (2023).

Metab Brain Dis.

DOI:

10.1007/s11011-023-01277-5

PubMed:

37646962

Obtaining polyphenolic extracts from pomegranate peel (Punica granatum) to evaluate the bactericide and antioxidant activity.

This study in Mexico analyzed three varieties of pomegranate peel and found that extracting polyphenols using acetone produced the best antioxidant and antibacterial results in the Apaseo variety. Useful for food or drug formulation.

Coronado-Reyes JA et al (2023).

An Acad Bras Cienc.

DOI:

10.1590/0001-3765202320200153

PubMed:

37646704