Immunology Studies

Thymoquinone Effect on Leishmania tropica/infantum and Leishmania-Infected Macrophages.

This study examines the effects of Thymoquinone, a compound found in Nigella Sativa, on Leishmania parasites and infected macrophages. It explores potential therapeutic benefits for Leishmania infection.

KarimiPourSaryazdi A et al (2023).
Acta Parasitol.
PubMed:
37589882

Chelidonine reduces IL-1β-induced inflammation and matrix catabolism in chondrocytes and attenuates cartilage degeneration and synovial inflammation in rats.

Chelidonine, extracted from Chelidonium majus, reduces inflammation and catabolism in osteoarthritis (OA) by inhibiting the NF-κB pathway, potentially preventing cartilage degeneration and synovial inflammation.

Li M et al (2023).
Braz J Med Biol Res.
PubMed:
37585914

Identification and expression analysis of MAPK cascade gene family in foxtail millet (Setaria italica).

This study identified 93 MAPK cascade genes in foxtail millet, divided into subgroups, and revealed their response to hormones and stress. Important for understanding plant growth and stress response.

Zhang L et al (2023).
Plant Signal Behav.
PubMed:
37585594

Immunomodulatory effect of glabridin in ovalbumin induced allergic asthma and its comparison with methylprednisolone in a preclinical rodent model.

Glabridin, a compound found in licorice roots, has anti-inflammatory and antioxidant properties. It can reduce inflammation, oxidative stress, and IgE antibodies in rats with allergic asthma. Further research and clinical trials are needed to evaluate its potential as a treatment for this condition.

Muhammad H et al (2023).
J Cell Biochem.
PubMed:
37584465

Neuroprotective Effects of Tinospora cordifolia via Reducing the Oxidative Stress and Mitochondrial Dysfunction against Rotenone-Induced PD Mice.

TCE extract protected against Parkinson's disease in mice by reducing oxidative stress, improving mitochondrial function, and reducing cell death. TCE could have potential as a neuroprotective treatment for Parkinson's disease.

Dilnashin H et al (2023).
ACS Chem Neurosci.
PubMed:
37579290

Sesquiterpene from Artemisia argyi seed extracts: A new anti-acute peritonitis agent that suppresses the MAPK pathway and promotes autophagy.

Scientists screened 18 types of Artemisia argyi seed extracts and found that CA-4 showed strong anti-inflammatory activity, promoting autophagy, and inhibiting pro-inflammatory factor production. It may be a potential treatment for acute inflammatory diseases.

Li Y et al (2023).
Inflammopharmacology.
PubMed:
37578619