Mechanistic Action of Cell Cycle Arrest and Intrinsic Apoptosis via Inhibiting Akt/mTOR and Activation of p38-MAPK Signaling Pathways in Hep3B Liver Cancer Cells by Prunetrin-A Flavonoid with Therapeutic Potential.

Prunetrin, a plant-derived compound, has shown anti-cancer properties in liver cancer cells. It decreases cell viability, arrests the cell cycle, promotes apoptosis, and inhibits signaling pathways. Promising potential treatment for hepatocellular carcinoma.

Abusaliya A et al (2023).

Nutrients.

DOI:

10.3390/nu15153407

PubMed:

37571343

Unripe Rubus occidentalis, Ellagic Acid, and Urolithin A Attenuate Inflammatory Responses in IL-1β-Stimulated A549 Cells and PMA-Stimulated Differentiated HL-60 Cells.

Unripe fruit contains polyphenols, including ellagic acid (EA), which improves type 2 inflammation and airway hyperresponsiveness in asthma. EA is converted to urolithin A (UA) by gut bacteria, which has anti-inflammatory properties. In this study, EA, unripe fruit water extract (uRO-w), and UA reduced inflammation and oxidative stress in lung and neutrophil cells, suggesting they could be used as treatments for respiratory diseases.

Kim S et al (2023).

Nutrients.

DOI:

10.3390/nu15153364

PubMed:

37571300

Solanum aethiopicum L. from the Basilicata Region Prevents Lipid Absorption, Fat Accumulation, Oxidative Stress, and Inflammation in OA-Treated HepG2 and Caco-2 Cell Lines.

Lela L et al (2023).

Plants (Basel).

DOI:

10.3390/plants12152859

PubMed:

37571013

Phytochemical Profiling, Antioxidant and Cognitive-Enhancing Effect of Helichrysum italicum ssp. italicum (Roth) G. Don (Asteraceae).

This study found that the methanol-aqueous extract from ssp. aerial parts has antioxidant properties and can improve memory and learning. It contains various compounds that can enhance cognitive function.

Gevrenova R et al (2023).

Plants (Basel).

DOI:

10.3390/plants12152755

PubMed:

37570911

Characterization of Portulaca oleracea Whole Plant: Evaluating Antioxidant, Anticancer, Antibacterial, and Antiviral Activities and Application as Quality Enhancer in Yogurt.

Purslane extract was added to yogurt, resulting in enhanced antioxidant, anticancer, antiviral, and antimicrobial properties. It also improved rats' body weight, liver parameters, and kidney function. Additionally, it improved the texture, color, flavor, and microbial content of the yogurt.

Al-Quwaie DA et al (2023).

Molecules.

DOI:

10.3390/molecules28155859

PubMed:

37570829

Terminalia bellirica Fruit Extract Alleviates DSS-Induced Ulcerative Colitis by Regulating Gut Microbiota, Inflammatory Mediators, and Cytokines.

This study found that ethyl acetate extract from fruits has anti-inflammatory effects and can alleviate symptoms of ulcerative colitis. It also suggests TBEA could be developed into a new drug for treating UC.

Li YY et al (2023).

Molecules.

DOI:

10.3390/molecules28155783

PubMed:

37570753

Determination of Active Ingredients, Mineral Composition and Antioxidant Properties of Hydroalcoholic Macerates of Vinca minor L. Plant from the Dobrogea Area.

This study analyzed the chemical and mineral composition of Vinca plant for use in dermal preparations. It found high concentrations of the bioactive compound vincamine and antioxidant activity. The plant also had low levels of toxic metals.

Neculai AM, Stanciu G and Mititelu M (2023).

Molecules.

DOI:

10.3390/molecules28155667

PubMed:

37570636

Effects of Traditional Chinese Herbal Feed Additive on Production Performance, Egg Quality, Antioxidant Capacity, Immunity and Intestinal Health of Laying Hens.

A Chinese herbal feed additive (TCM) improved egg production, quality, antioxidant capacity, immunity, and intestinal health in Roman laying hens compared to control and antibiotic groups.

Liu B et al (2023).

Animals (Basel).

DOI:

10.3390/ani13152510

PubMed:

37570319