Immunology Studies

Safranal inhibits estrogen-deficiency osteoporosis by targeting Sirt1 to interfere with NF-κB acetylation.

Safranal, derived from Saffron, has anti-inflammatory properties. Its role in osteoporosis, a bone disease in menopause, and its effect on osteoclasts regulated by NF-κB signaling is unknown.

Sheng SR et al (2023).
Phytomedicine.
PubMed:
37004404