Huangqin Decoction ameliorates ulcerative colitis by regulating fatty acid metabolism to mediate macrophage polarization via activating FFAR4-AMPK-PPARα pathway.
- Li MY et al (2023).
- J Ethnopharmacol.
- PubMed:
- 36997133
Researchers analyzed the chemical contents of methanolic crude extract and its fractions (ethyl acetate, n-butanol, aqueous) using LC-MS analysis. They then tested the antioxidant properties (via DPPH, ABTS, etc. assays) and ability to inhibit enzymes (AChE, BChE, etc.). The study highlights the potential pharmacological properties of the extract and its potential for use in alternative medicine.
Researchers evaluated the effects of Eryngium carlinae, a plant used in Mexican traditional medicine to treat diabetes, on brain function in diabetic rats. They used green synthesis to make nanoparticles that enhance the plant's properties. Results showed that both the plant extract and its nanoparticle combination reduced the production of reactive oxygen species, lipid peroxidation and restored mitochondrial function in the brain. The extract-nanoparticle combination also decreased blood glucose and triglyceride levels. These findings suggest that both treatments could be beneficial for treating diabetes.