Potential immunomodulatory response associated with L-mimosine in male Wistar rats.

Hueza IM et al (2023).

Toxicon.

DOI:

10.1016/j.toxicon.2023.107084

PubMed:

36905965

Withania somnifera influences MDMA-induced hyperthermic, cognitive, neurotoxic and neuroinflammatory effects in mice.

This study investigated the effects of Withania somnifera (WS) in preventing the neurotoxicity and memory impairments caused by MDMA. Mice were pretreated with vehicle or WSE before being randomly assigned into four groups: saline, WSE, MDMA alone, or WSE plus MDMA. Mice that were treated with only MDMA showed a decrease in dopamine levels and an increase in gliosis and hyperthermia, leading to memory impairments, while mice treated with both WSE and MDMA showed protection against the noxious effects of MDMA. This study suggests that WSE may be beneficial in counteracting the harmful effects of MDMA on the brain.

Costa G et al (2023).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2023.114475

PubMed:

36905810

Physicochemical Characterization and Antioxidant Properties of Chitosan and Sodium Alginate Based Films Incorporated with Ficus Extract.

Bhatia S et al (2023).

Polymers (Basel).

DOI:

10.3390/polym15051215

PubMed:

36904456

Water Extract of Chrysanthemum indicum L. Flower Inhibits Capsaicin-Induced Systemic Low-Grade Inflammation by Modulating Gut Microbiota and Short-Chain Fatty Acids.

Yang B et al (2023).

Nutrients.

DOI:

10.3390/nu15051069

PubMed:

36904069

Design of an Herbal Preparation Composed by a Combination of Ruscus aculeatus L. and Vitis vinifera L. Extracts, Magnolol and Diosmetin to Address Chronic Venous Diseases through an Anti-Inflammatory Effect and AP-1 Modulation.

Nocera R et al (2023).

Plants (Basel).

DOI:

10.3390/plants12051051

PubMed:

36903912

Isolation, Bioactive Potential, and Application of Essential Oils and Terpenoid-Rich Extracts as Effective Antioxidant and Antimicrobial Agents in Meat and Meat Products.

Šojić B et al (2023).

Molecules.

DOI:

10.3390/molecules28052293

PubMed:

36903538

Two Ferulic Acid Derivatives Inhibit Neuroinflammatory Response in Human HMC3 Microglial Cells via NF-κB Signaling Pathway.

Scientists investigated the potential of two compounds from a plant extract in reducing inflammation related to neurodegenerative diseases. Using a human microglial cell model, they found that trans-ferulic acid and methyl ferulate significantly reduced the production of inflammatory mediators and increased levels of an anti-inflammatory factor. Additionally, the compounds inhibited the activation of a signaling pathway involved in inflammation. These findings suggest that the compounds could be useful in treating neuroinflammatory diseases.

Li PL et al (2023).

Molecules.

DOI:

10.3390/molecules28052080

PubMed:

36903325

Flavonoids from the Roots of Sophora flavescens and Their Potential Anti-Inflammatory and Antiproliferative Activities.

Yang YF et al (2023).

Molecules.

DOI:

10.3390/molecules28052048

PubMed:

36903293