Immunology Studies

Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-κB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism.

Cardile A et al (2023).
Int J Mol Sci.
PubMed:
36674794

Actaea racemosa L. Rhizome Protect against MPTP-Induced Neurotoxicity in Mice by Modulating Oxidative Stress and Neuroinflammation.

A natural compound found in L. rhizome may alleviate symptoms of Parkinson's disease (PD) by reducing oxidative stress and modulating inflammatory indicators involved in the disease, according to a study on an in vivo model. Mice with PD were treated with L. rhizome for seven days, and the treatment reduced the degeneration of dopaminergic neurons and improved motor and non-motor deficits. L. rhizome may offer a promising dietary supplement to improve brain health and slow the course and symptoms of PD.

Cordaro M et al (2022).
Antioxidants (Basel).
PubMed:
36670902