Immunology Studies

Effect of ultrasonic degradation on the physicochemical characteristics, GLP-1 secretion, and antioxidant capacity of Polygonatum cyrtonema polysaccharide.

Ultrasonic degradation of Polygonatum cyrtonema polysaccharide alters physical and biological properties without changing structure, enhancing bioactivity for GLP-1 secretion, antioxidant, and enzyme inhibition. Controlled ultrasound can improve PCP as a functional agent.

Liu W et al (2024).
Int J Biol Macromol.
PubMed:
38936570

Psidium guajav-mediated zinc oxide nanoparticles as a multifunctional, microbicidal, antioxidant and antiproliferative agent against destructive pathogens.

Zinc oxide nanoparticles from plant extract show antimicrobial, antioxidant, and antiproliferative properties, with potential for drug research and targeted cancer treatments.

Thejashwini PP et al (2024).
Bioprocess Biosyst Eng.
PubMed:
38935113

Antioxidant and antibacterial effects of a new macrocyclic bis(bibenzyl) ether from Combretum molle (Combretaceae).

New compounds and sterols isolated from plant root exhibited moderate antioxidant and antibacterial activities, showing potential for use in pharmaceuticals and health products. Antibacterial activity against specific strains at low concentrations. Concentration-dependent effectiveness.

Yakai F et al (2024).
Z Naturforsch C J Biosci.
PubMed:
38934447

Inhibition of SARS-CoV-2-Induced NLRP3 Inflammasome-Mediated Lung Cell Inflammation by Triphala-Loaded Nanoparticle Targeting Spike Glycoprotein S1.

Nanoparticles loaded with Triphala (nanotriphala) show promise as a anti-inflammatory therapy for COVID-19. Chebulagic acid and chebulinic acid are the active compounds reducing cytokine release and inflammation.

Chittasupho C et al (2024).
Pharmaceutics.
PubMed:
38931873

Comparative In Vitro Study: Assessing Phytochemical, Antioxidant, Antimicrobial, and Anticancer Properties of Vaccinium macrocarpon Aiton and Vaccinium oxycoccos L. Fruit Extracts.

Study investigated phytochemicals in and fruits, finding cranberry extracts had higher antioxidant activity and inhibited bacterial growth. Cranberry fruit extracts also showed cytotoxicity against prostate and renal cancer cells, suggesting potential for natural remedies in bacterial infections and cancer therapy.

Šedbarė R et al (2024).
Pharmaceutics.
PubMed:
38931857

Phenolic Composition of Crataegus monogyna Jacq. Extract and Its Anti-Inflammatory, Hepatoprotective, and Antileukemia Effects.

Study investigated potential benefits of plant () in traditional medicine: anti-inflammatory, hepatoprotective, and anticancer properties. Promising results suggest further exploration for liver damage, inflammation, and leukemia treatment.

Ez-Zahra Amrati F et al (2024).
Pharmaceuticals (Basel).
PubMed:
38931453

The Neuroprotective Effects of Oroxylum indicum Extract in SHSY-5Y Neuronal Cells by Upregulating BDNF Gene Expression under LPS Induced Inflammation.

Researchers found an herbal extract called Sabroxy can significantly increase BDNF expression, supporting neuronal health and protecting against inflammation. Sabroxy's antioxidant properties could mitigate neurodegeneration damage. This suggests a potential therapeutic application for neurological disorders.

Sreedharan S et al (2024).
Nutrients.
PubMed:
38931243