Neuroscience Studies

Therapeutic effects of rosemary (Rosmarinus officinalis L.) and its active constituents on nervous system disorders.

Rosemary is an evergreen shrub used in folk medicine to treat various conditions. Studies highlight that it has significant neuropharmacological properties, including antimicrobial, anti-inflammatory, anti-oxidant, and neuroprotective effects. It also shows clinical benefits for mood, memory, pain, anxiety, and sleep. The aim of this review is to evaluate the preclinical potential of rosemary extracts and its active constituents on nervous system disorders. The study includes various sources from PubMed, Scopus, Google Scholar, and Web of Science without any time limitation. The review finds rosemary as a potential source for inflammation, analgesic, anti-anxiety, and memory-boosting therapeutics. The study recommends further research on isolated constituents such as carnosic acid, rosmarinic acid, and essential oil to help people with nervous system disorders.

Neuroscience Rosmarinus officinalis
Ghasemzadeh Rahbardar M and Hosseinzadeh H (2020).
Iran J Basic Med Sci.
DOI:
10.22038/ijbms.2020.45269.10541
PubMed:
32963731

Neuroprotective potential of Myrica esulenta in Haloperidol induced Parkinson's disease.

Myrica esculenta is a medicinal plant commonly used in Indian traditional medicine for various ailments. The fruit and bark of the plant have been used to treat a range of conditions, including fever, diarrhea, and respiratory problems. Ayurvedic literature also suggests its use in conditions such as anemia, mouth and throat infections, and digestive disorders.

Neuroscience Myrica esculenta
Kabra A et al (2020).
J Ayurveda Integr Med.
DOI:
10.1016/j.jaim.2020.06.007
PubMed:
32912644

Acteoside Isolated from Colebrookea oppositifolia Smith Attenuates Epilepsy in Mice Via Modulation of Gamma-Aminobutyric Acid Pathways.

Acteoside was evaluated for its anticonvulsant properties and mechanism of action in mice. It was found to have significant anticonvulsant activity in the pentylenetetrazole (PTZ) model, but not in the maximal electroshock (MES) or N-methyl-D-aspartic acid (NMDA) models. Studies on the PTZ model showed that acteoside restored altered antioxidant levels, GABA mRNA levels, and glutamate levels in the cortex and hippocampus regions of PTZ-treated mice. The anticonvulsant activity of acteoside was confirmed to be due to its GABAergic mechanism and was found to have no central side effects. The study concludes that acteoside and related compounds may be useful in the treatment of epilepsy.

Neuroscience Colebrookea oppositifolia
Viswanatha GL et al (2020).
Neurotox Res.
DOI:
10.1007/s12640-020-00267-0
PubMed:
32803629

Herbal Medicinal Products from Passiflora for Anxiety: An Unexploited Potential.

Herbal medicines containing species have been used for anxiety treatment for centuries. This study investigated the uses of the main species of the genus with anxiolytic activity, secondary metabolites and pharmacological studies. Results indicate that species have health benefits, but clinical trials are still scarce. is the most studied species and the most used in natural anxiolytic herbal medicine formulations. However, there are hundreds of species potentially useful for medicinal and nutraceutical purposes that remain little explored. The complexity of extracts creates challenges for the development of herbal medicines.

Neuroscience Passiflora incarnata
da Fonseca LR et al (2020).
ScientificWorldJournal.
DOI:
10.1155/2020/6598434
PubMed:
32765195
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