The mechanism of neuroprotective effect of Viola odorata against serum/glucose deprivation-induced PC12 cell death.

This study aimed to investigate the antioxidant potential of L in protecting brain cells from damage due to reduced oxygen supply and glucose. Researchers tested the methanol extract and other isolated fractions of L in PC12 cells subjected to serum and glucose deprivation. The results showed that the extract and fractions had significant neuro-protective effects and could scavenge reactive oxygen species. Overall, this study suggests that L may have a potential role in the management of oxidative stress-related neurodegenerative disorders.

Tayarani-Najaran Z et al (2019).

Avicenna J Phytomed.

DOI:

10.22038/AJP.2019.13098

PubMed:

31763208

Saffron (Crocus sativus L.): A Phytomedicine as Effective as Methylphenidate in Treating ADHD in Children.

Ross SM et al (2020).

Holist Nurs Pract.

DOI:

10.1097/HNP.0000000000000365

PubMed:

31725101

Protaetia (Potosia) jelineki (Coleoptera: Scarabaeidae: Cetoniinae: Cetoniini): preimaginal stages, biology, intrapopulation variability and taxonomy.

In this study, researchers described the previously little-known flower beetle Protaetia (Potosia) jelineki from north-eastern Turkey. They provided detailed descriptions and illustrations of the beetle's larvae and pupae, as well as information on the variation seen in the adult population. The researchers also discussed the identity of a previously known syntype, and introduced a new character for diagnostic purposes. The natural history of P. jelineki was also documented, including its association with flowering plants and activity periods. This study provides valuable contributions to the taxonomic knowledge of P. jelineki.

Uliana M, Vas'ko B and Polat A (2019).

Zootaxa.

DOI:

10.11646/zootaxa.4565.1.7

PubMed:

31716493

Description of Harpactea popovi sp. n. from Bulgaria with further taxonomic notes on related species (Araneae, Dysderidae).

A new species of spider, Harpactea popovi, has been discovered in beech forest habitats in Southeastern Bulgaria. The spider belongs to the Harpactea rubicunda species group and is closely related to two other species. The study establishes two synonymies. Illustrations and photographs of the new species are provided.

Dimitrov D, Deltshev C and Lazarov S (2019).

Zootaxa.

DOI:

10.11646/zootaxa.4568.3.13

PubMed:

31715854

A botanical drug composed of three herbal materials attenuates the sensorimotor gating deficit and cognitive impairment induced by MK-801 in mice.

Researchers investigated the effects of a botanical drug derived from three plants on schizophrenia-like behaviors induced by MK-801. The drug has been used to treat rheumatoid arthritis in Korea. The study found that the herbal complex extract improved cognitive function and reduced the symptoms of schizophrenia-like behaviors in mice. These results suggest that the botanical drug could potentially be used to treat schizophrenia in humans.

Koo B et al (2020).

J Pharm Pharmacol.

DOI:

10.1111/jphp.13199

PubMed:

31713882

Lycodine-type alkaloids from Lycopodiastrum casuarinoides and their acetylcholinesterase inhibitory activity.

Researchers identified five new alkaloids and ten known analogues in Lycopodiastrum casuarinoides, a plant commonly used in traditional Chinese medicine to improve cognitive function. Spectroscopic techniques were used to determine the structures of the novel compounds and their absolute configurations. Only huperzine C showed moderate inhibitory activity against acetylcholinesterase, which is associated with Alzheimer's disease. The study highlights the potential of Lycopodiastrum casuarinoides as a source for developing new drugs to treat cognitive impairment.

Feng Z et al (2019).

Fitoterapia.

DOI:

10.1016/j.fitote.2019.104378

PubMed:

31676395

Artemisia dracunculus L. modulates the immune system in a multiple sclerosis mouse model.

Researchers investigated the effects of tarragon extract on experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis. Female mice were divided into groups and EAE was induced. Mice were treated with tarragon extract or left untreated. Symptoms of EAE were recorded daily and specimens were collected on day 33. Results showed that tarragon extract reduced EAE symptoms and levels of inflammatory cytokines IL-17 and IL-23. It also increased serum antioxidant levels. These findings suggest the potential of tarragon extract as an adjuvant therapy for MS.

Safari H, Anani Sarab G and Naseri M (2021).

Nutr Neurosci.

DOI:

10.1080/1028415X.2019.1681742

PubMed:

31665978

Medicinal Plants in the Treatment of Obsessive-Compulsive Disorder: A Review.

This study investigated the potential effectiveness of an herbal remedy called ashwagandha root extract in treating OCD. They conducted a double-blind, randomized, placebo-controlled trial with 60 participants over 12 weeks. The group taking the ashwagandha extract showed significant reduction in OCD symptoms compared to the placebo group. The researchers conclude that ashwagandha may be a promising herbal remedy for OCD treatment. However, more research is needed to confirm these findings and determine the long-term safety and effectiveness.

Talaei A, Forouzanfar F and Akhondzadeh S (2021).

Curr Drug Discov Technol.

DOI:

10.2174/1570163816666191011105050

PubMed:

31660838