Researchers investigated the use of non-pharmacological interventions for neuropathic pain as an alternative to current drugs. Their findings may offer more effective and safer treatment options for patients.
Lysionotin, a natural flavonoid from the plant Maxim, was studied for its pain-relieving properties. It showed potential as an analgesic, indicating possible use as a treatment for pain-related conditions.
Excelsatoxin A (ExTxA), a plant-derived toxin, interacts with sodium (Na) channels in sensory neurons. TMEM233 is an essential protein for ExTxA's effects on Na channel gating, providing insights into sensory neuron function.
Researchers studied the effects of henna oil on chronic sciatica. Henna oil is often recommended in traditional medicine for pain relief. Understanding its effectiveness can help with managing sciatica and improving patient care.
The study found that ECa 233, a Centella asiatica extract, reduces inflammation and pain in mice with temporomandibular disorder (TMD). It may be a safe alternative treatment with maximum effectiveness at a dosage of 100 mg/kg.
CBD reduced anxiety, pain hypersensitivity, and anhedonic behavior in mice with a partner in chronic pain. It also reversed chronic pain-induced anxiety and improved withdrawal thresholds, grooming behavior, and the partner's symptoms. CBD may help alleviate pain-related symptoms in individuals and their close contacts.
Researchers developed evidence-based guidelines for patient selection and the role of a spinal cord stimulation (SCS) trial for neuropathic pain relief. These recommendations should help guide physicians in selecting patients for SCS therapy.
This study tested the efficacy and safety of PE extracts for relieving knee joint pain and improving function. Results showed that PFE intake for 8 weeks was more effective than placebo without major safety concerns.